Document km2X4LBZx60av6BmdB8O3KLLq
* ^%
'
CONFIDENTIAL
RECetVBt)
R'W.Huse
WORLD
REGI S IER
OF
CASES
OF
angiosarcoma
OF
liver
(a s l)
the
REVIEW DATE
1 JANUARY 1988
*********
Collated by:
Dr Brian Bennett
``
Occupational Health Department
ICI Chemicals and Polymers Limited
Hillhouse Site PO Box 4
Thornton-Cleveleys
Blackpool
FY4 4QD
England
(Telephone (Telex .(Facsimile
0253 861632 ) 67483 ICIPLHG)
0253 861861 )
GENC 008189
tykVUi\ i'il'KlLUOCU'^jL'it'L IVAjJlij
CIRCULATION OF REGISTER
UJWf UJCJN11AL.
tLBKUAKY 1988
RAGSHAW Dr I M M RAND Dr P R BARON Dr C BARRAT Dr G BAXTER Dr Peter BAYLAC Dr REAUPRE M BELLEC Dr BENEffl Dr M BENNETT Dr B BEKTAZZI Dr P BISHOP Dr C 80RRELLI F E BOYER R W BRAUN Dr C L J BREWER Dr M BRYSON Dr D D BURGESS Mr David BYREN Dr David CARTER Dr J T CATANEARITI A CELIA Mr C CHANCE Mr M CLAHCE Dr E A CLAUS Mr P G CLAYTON Mr H OONTASSOT Dr J C DAVIES Mr J G DEJONG Dr G DELORME Dr F DEPLAN Dr DE VOS Mr A J DIETZ Dr H W DOLL Sir Richard DOMBROWSKI S L DRLMWRIGHT Dr J R DUPONT Mr G EMMINGER Mr H ERNST Dr W EVANS Dr A E J FALK, Dr H FAVRE Dr FERGUSON Dr D M ETNOTAM Ms Shirley FORMAN Dr D FRASE R W FRIEDEL Dr H P GOSZTONYI Jnr Dr GOTTE91AN R T HARRIS Dr W D HENDERSON I B HILLMAN Dr D W HINDERER Dr R K HOWARD Dr J K HUMPHRY Dr N F JAUVEKT Mr J JERVIS HHR JONES Dr R D
Norsk Hydro, Newton Aycliffe, UK Cancer Control Agency of British Cblunbia, Vancouver, Canada ICI Runcorn, UK AECRP, Gontnentry, France University of Canbridge, UK Atochem, Chauny, France Government of Quebec Cancer Registry, Canada Krone Poulenc, Aubervillers, France Naphtachinde, Lavera, France ICI Hillhouse, UK Inst of Occupational Health, MLlan University, Italy EMAS, Cardiff, UK Georgia Gulf, Delaware City, USA Formosa Plastics, Delaware City, USA Akzo, Amhen, Holland Imperial Oil, Sarnia, Ontario, Canada ICI Billinghim, UK
ICI Americas, Wilmington, Delaware USA Kiemanord, Stockholm, Swden EMAS, London, UK EVC, Brussels, Belgiun EVC, Brussels, Belgium ICI Runcorn, UK Ontario Cancer Foundation, Toronto, Canada APME, Brussels, Belgiun Norsk Hydro, Newton Aycliffe, UK Atochem, Saint-Fons, France ICI, Everberg, Belgiun Shell, An Den Haag, Holland Quebec, Canada Atochem, Jarrie, France EVC, Welwyn Garden City, UK B F Goodrich, Akron, Ohio, USA Imperial Cancer Research Fund, Oxford University, UK Dow Chemical, Midland, Michigan, USA Vista Chemical, Houston, Texas, USA APME, Brussels, Belgiun VKE, Frankfurt, Germany Berufsgenossenschaft der Chsnischen Industries, Nurnberg, Germany Lever Bros, Warrington, UK Chronic Diseases Div, US Dept of Health & liman Services, Atlanta, USA Atochsn, Montluel, France ICI Americas, Wilmington, Delaware, USA Alberta Cancer Board, Edmonton, Canada Imperial Cancer Research Ednd, Oxford University, UK DtversiTech General, Akron, Ohio, USA Berufsgenossenschaft der Chsnischen Industries, Heidelberg, Gsnany R E Tenneco Chemicals, Piscataway, New Jersey, USA The Vinyl Institute, Wayne, NJ, USA Uniroyal Inc, Middlebury, Connecticut, USA ICI, Hillhouse, UK Diamond Shamrock Corp, Dallas, Texas, USA BF Goodrich, Cleveland, Chio, USA University of Otago School of Medicine, Wellington, New Zealand ICI Australia, Melbourne, Australia Chloe Chimie, Paris, France ICI Millbank, London UK EMAS, Bootle, UK
WPX/ASL - ASL ADDRESS,!
OENC 008190
I1
KAIPEKT Dr JH KARRH Dr Bruce KLEIN Dr H KREUGER Dr R A LAGAST Dr H LALOINE Dr J P LANHAM Dr John LANOUZIERE Dr IAWRENCE-JONES LEE Dr F I LELBACH Prof WC LEVBQUE Dr G LEVISON Dr D A LEWIS Dr P L0LIV1ER Mr LUSS R D LUSSAIO Dr Josette MAILLARD Dr J M MALTONI Prof C MARGETTS, Mr R J MATIRE Prof Lo MATmiSSI Dr R MIDDLETON D MOKKA Mr MONIESANO Dr R MDTTI Dr A A MJNCE MOUTCN Dr M MacStEEN Prof RMI NAKAMJRA Dr S OLSON H G CWEN Dr R PADDLE Dr G M PtfILIALUNGA Dr S PAQUET Dr FATERSCN Dr J C PIRASIU Dr Roberta POPPER Dr Hans POSSBERG Dr J PUECH Dr A M PURDHAM Dr J RAMBAUD Dr J RICHARD Dr P ROBSCN Mrs D RODRIGUES Dr MJF ROUSH Dr G RUTY Dr J SAIG Dr Joyce A SARAOCI Dr R SCHEFFERS Dr T M L SCHIPPER Dr H SERONNE Dr D SHAH Dr Has SIGRIST Dr J SMITH Prof Allan H SMITH Dr E SMITH It J S SMITH Dr P M SPHfEAS Dr R STAFFORD Dr J STAHNECXER Mr SULAIMAN Dr
-z-
Dow Chemical Europe, Horgen, Switzerland Dupont, Wilmington, Delaware USA Dynamit Nobel, Troisdorf, Germany BF Goodrich, Akron, Ohio, USA Saivay, Brussels, Belgiun Solvay, Brussels, Belgiun Dow Chemical, Midland, Michigan, USA Solvay, TSvaux, France Sir Christopher, Chief Medical Officer, ICI, London UK Victoria Hospital, Blackpool, Lancs, UK University of Bonn, West Germany CDF Chimie, AZF, Bully-les-MLnes, France St Bartholomew's Hospital, London, UK Chemical Industries Association, London, UK Solvay, Brussels, Belgiun Occidental Chemical, Pottstown, Pennsylvania, USA Atochan, France Suva, Luzern, Switzerland Institute di Oncologia, Bologna, Italy ICI Directorate, Wilton HQ, UK Medil-Anic-S, Milan, Italy Montedison, Milan, Italy Norsk Hydro, Newton Aycliffe, UK Neste Oy, Espoo, Finland IARC, Lyon, France Duperial SAIC, Buenos Aires, Argentina Rio Rodano, Madrid, Spain Western Infirmary, Glasgow, Scotland Japanese PVC Association, Tdcyo VC Safety Association, Louisiana, USA Trades Union Congress, London, UK ICI Central Medical Group, Alderley Park, UK Montedison, Novara, Italy Atochan, Senquigny, France ICI Runcorn, UK Istltuto Superiore di Sanita, Rone, Italy Mount Sinai Medical Center, New York, USA Wacker-Chanie, Munich, Germany Atochan, Brignoud, France Canadian Centre for Occupational Health & Safety, feniltoi, Canada RP Recherches, Antony, France Phone Poulenc, Roussillon, France Saskatchewan Cancer Foundation, Regina, Canada ICI, Sao Paulo, Brazil Monsanto, St Louis, Missouri, USA Atochem, St Auban, France N10SH, Cincinnati, USA IARC, Lyon, France DSM/CVMD, Geleen, Holland University of thnitoba, Winnipeg, Canada Diamond Shamrock, Dallas, USA CMA, Washington DC, USA Shell Chimie, Berre L'Etang, France University of California, Berkeley, USA Division of Envirornental Health, World Health Organisation, Geneva, Switzerland ICI Hillhouse, UK LLandough Hospital, Penarth, UK NCI/NIH, Bethesda, Fhryland, USA Somerset, UK BASF, Ludwigshafen, Germany Arabian Petrochemical Co, Saudi Arabia
WPX/ASL - ASL ADDRESS,2
1
GENC 008191
TACHECI Dr H TAMBURRO Prof CH ten BERGE DrWF TENKHOFF Dr N TEPPER Dr L B TER HAAR Dr Gary TERWIESCH Dr B THERIAULT Dr Gilles THIESS Prof Dr A M THIIS-EVEN5EN Dr E THCMSON Dr D H TONER H P VAN DER MER1* Dr H J WALLACE J R WALTEMATE H WEJELING S 0 WHITE K H wit,Drarr 0 WILLIAMS Dr DMJ WILSON Prof R WRIGHT Dr A P YORK J
Hoechst AG, Frankfurt, Germany University of Louisville, USA DSM, Geleen, Holland Tills AG, Efarl, Germany Air Products, Allentown, Pennsylvania, USA Ethyl Corporation, Baton Rouge, Louisiana, USA Chemische Vferke Tills, Kreis Recklinghausen, Germany TfcGill University, Montreal, Canada BASF, Ludwigshhafen, Germany Norsk Hydro, Porsgrunn, Norway Cancer Treatment & Ttesearch Foundation, Halifay, NS, Canada Society of the Plastics Industry, Washington DC, USA AECI, Sasolburg, South Africa Esso, Sarnia, Ontario, Canada BF Goodrich, Cleveland, Ohio, Usa Norsk Hydro, Stenungsund, Sweden Duperial, Buenos Aires, Argentina Electrochenical Industries, Aire, Israel EP Chemicals, Penarth, UK Harvard University, Canbridge, Massachusetts, USA IQ Wilton, UK ICI Everberg', Belgian
Fran: Dr B Bennett, Occupational Health Department, ICI Chanicals & Polymers Group, Hlllhouse Site, PO Box 4, Thomton-develeys, Blackpool FY5 4QD, England
WPX/ASL - ASL ADDRESS,3
CONFIDENTIAL REGISTER OF CASES OF ANGIOSARCOMA OF THE LIVER DUE TO EXPOSURE TO VINYL CHLORIDE - REVIEW DATE 1 JANUARY 1988 PREFACE : ACKNOWLEDGMENTS, SIGNIFICANT CHANGES, COMMENTS AND REQUESTS
1 The 8 new cases in the Register are the following: Canada 11 and 12; France 22; Italy 06; Japan 03; UK 14; US 40 and 1
2 There are amendments from the previous Register against the following cases: Japan 01 and 02.
3 I would like to thank the following for informing me of new cases: Dr Delorme, Dr Contassot, Dr Chiozzini, Dr Nakamura, Dr Evans, Dr Williams, Dr Dietz, and Professor Tamburro.
4 For the case corrections I thank Dr Nakamura.
5 It will be noted that there are gaps in our knowledge of several cases, notably Canada 11 and 12 and US 4l. Also, so far as we know the following people are still alive: cases Canada 11, France 15 and 22, Germany 31 and 32, UK 14, US 33, 36, 4] Is this correct? This is important information for the industry world-wide and we would appreciate news.
6 I should be glad if all recipients of the Register would continue to keep me fully informed of any new cases, or give the name and address of someone who can give me the necessary details. I have again attached a blank sheet at the back of the Register so that information can be supplied under the appropriate headings, so far as possible.
7 As a result of the request sent with last year's Register, regarding Co-factors, we received a great deal ofinformation about PVC Plants, which has resulted in many amendments to Tables 8, 9, 10 and 13. Further corrections will be appreciated, bearing in mind that the Tables are confined to PVC.
8 RESEARCH: (a) May I again ask that all individuals involved in relevant research keep me informed and if possible send me reports. Perhaps recipients of this Register would pass on my request.
(b)
Co-factors: In response to the questionnaire enclosed with the 1987 Register, regarding possible co
factors with Vinyl Chloride, I received replies from 26 Companies, covering 6l factories. This material is now being analysed by Professor Carlo Tamburro at the University of Louisville, Kentucky, USA, and we shall report on the results as soon as possible. We are extremely grateful to all who took the trouble to give this information. If any Company has not yet completed the Co-factor questionnaire I should be grateful if it could be completed and sent back to me as soon as possible.
9 I would also be glad of help to keep the mailing list correct and up to date, with news of retirements, etc.
FROM: Dr Brian Bennett, Occupational Health Department, ICI Chemicals and Polymers Limited Hillhouse Site, P 0 Box 4, Thornton-Cleveleys, Blackpool, FY5 4QD, England
February 1988
BB/BGS
fcAM
'
Index
Table Sequence
Belgium
Canada
Czechoslovakia
France Germany
Italy
Japan
Norway
Sweden
UK
USA
Yugoslavia
Incidence of Cases per annum (Table 1)
Distribution of Cases
by Country
(Table 2)
Pattern of Cases by
Factory
(Table 3}
Latency Periods (Table 4A)
Distribution of Latency Periods (Tables 4B-4H)
Annual Geographical Incidence (Table 5)
1CI CHEMICALS 6 POLYMERS
WPX/ASO - LANGIOCASES,4
LIVER ANGIOSARCOMA CASES (REVIEW DATE - I JANUARY 1988)
1
Page
1
1 |
1 1 ASL Case Numbers by year of Death
2-3
1 1
(Table 6)
1 ASL Case Numbers by year of first exposure
4t
(Table 7)
5-9
1 1 Western Europe PVC Producers - Start-up Dates vs ASL Cases
10-15
1 1
(Table 8)
1 USA PVC Producers - Start-up Dates vs ASL Cases
16-17
1 j
(Table 9)
18 1 Canadian PVC Producers - Start-up Dates vs ASL Cases
1 (Table 10)
19 1
1 East European PVC Producers - Start-up Dates vs ASL Cases
20 1
(Table 11)
Page 46 47 48-49 50-51 52 53
21-24 25-32
33
! 1 1 1 1
Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12)
South A Central American PVC Producers - Start-Up Dates (Table 13)
54 55
34 1 Australasian PVC Producers - Start-up Dates 1 (Table 14)
56
35 Middle Eastern PVC Producers - Start-up Dates I (Table 15)
36 1 Blank form for notifying new cases 1
57 -
37 1
38-44 45
1 I
j
1
1 1
i (3EMC 0031'?4
Pane I
BELGIUM
TCI CHEMICALS & POLYMERS LIVER Angiosarcoma Cases - (Review Date ; L January 1988)
VPX/ASL - LANGIOCASES 6
' COUNTRY AND
REFERENCE NO
BELGIUM 01
02
23
NAME OR INITIALS
DATE OF BIRTH
12.01.13
SR 29 09 40
4 15 COMPANY [ FACTORY
Solvay
| Jemeppe
Solvay
| Jemeppe
6
7
0|
9
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT j YEARS OF DIAGNOSIS | EXPOSURE TO
DIAGNOSIS
00.07.58 00.05,76
63 |
18
20 08 82 00,10.79
39 |
17
________ L
10 1 11 YEARS OR I DATE OF EXPOSURE | DEATH
t 17 |29,06.76
t 9 123 10 83
j___________
11
12
13 I
14 |
15
1
16
11
HISTOLOGICAL CONFIRMATION
ESTIMATED |
|
EXPOSURE j OCCUPATION |
LEVEL |
[
OTHER CAREER HIGHLIGHTS
| [
OTHER COMMENTS
1i
11
\1
jt Yea High |Autocleaner |Driller in a (Hepatic testa
114 yrs
|foundry
jIn Oct 1974
1958-1968 \
|(2 yrs)
Iwere normal.
exposed to| Polyworker | Fanner
|Retired
200 ppm |3 yra
|(I5 yrs)
1Feh 1975
for 8 hrs |
[Work. In glass |Hospitalised
per day |
jind, 6 cheai- iMay 1976
and |
jcal Industry
certainly j
|
|Complete
under
|
|
ICllnlcal and
500 ppm |
|
[career detail
In 6 to 9.3
| |
| j
jare given in Ipaper by
autoclaveal
|
[Hublet et si
1968-1972 1
|
j In Arch. Self
exposed toj 50-200 ppn|
| |
j Med. Soc. , IKyg. Ked.
8 hrs per |
\
|Trav. Med.
day In 25m3
| 1
[ 1
1 Leg. I 1977 pages
autoclaveal
I
[601-622
1972-1974 |
]
exposed to|
J
50-200 ppm]
I
in auto- t
1
clave room|
[
1974-100 1
|
PP*n 1 1975- 50 \ ppm | RETIRED [
1 Feb 19751
1 | | |
|
I1 i1 Yes 08.62-03. 1 Autocleaner )Flreman since 11st sign July
63 01.67 |5 yrs 5 mths|10 71.
(79: Thoracic
-10.71 * |Operator
|
(pain 07.79.
200 ppm |3 yrs 9mtha.|
IHepatlc tests
8h/day
J
|
(sltered 10.79
04,63-12. |
|
|Positive
66 < 200 |
\
(echography
Ppm 1
1
J J1.79. Hepa-
11
Itectomy 02.80
11
|Chemotherapy.
11
FInformatlon
1f
Iglven In
1J
lletter 12 Nov
11 ---------------------- 1------------------------- 1
11964 f rom Dr |De Sloover.
GENC 003195
Page 2
CAN ADA Sheet J
LIVER Angiosarcoma Cases - (Review Date: 1 Jan 1988)
DAY - MONTH - YEAR
WFA/ASL - LANGiUUAbtlj,
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
13 14
15
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EX POSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
I
ESTIMATED j
EXPOSURE| OCCUPATION |
LEVEL
|
I
f OTHER CAREER
| HIGHLIGHTS
l J
I
OTHER COMMENTS
01 t 1 1 1
02 E 1 1 J I
03 1 1 1 1 I
04 1
1 1 1 1
1 05 1
l 1 1 1 06 1 1 1 f 1 07 1 1 1 i 1 08 1 1 1 1 09 1 1 1 1
115.12.13 1 1i li 1i 106.03.14 1 1r 1i 1i 1i 126.08.19 i 1i 1i ii li 105.04.19 i
Ii
!i 1i 1i
1i 107.05.11 i
1i r
1i 1i 1J5.12.19 i 1i 1i 1i 1! 109.11.19 J !1 11 i1 ]1 113.05.20 1 11 1F 11 119.07.2l I 1l 11 11
1
i 1944
1955
41 t L i
1 " 102.09.55
Yes |
1l
1 1f
1
1l
1 11
1
l
1
1 1943
1957
43
11 14 i 14 121.12.57
f Yes |
fi
1i
1l
1\
1
l 1941
1962
42
i1 i1 i1 i1 21 i 20 123.03.62
1 1
! 1 Yes J
1\
El
Jl
1l
1
1 1945
1967
4B
lf i1
11 l1 22 1 22 121.01,68
1 l 1
1 Yes |
1E 11 1l 11
l1 l1 11 lF
i 1 1 1
11
i
1
1 1944 i 1968
57
l1 24 1 05 105.07.68
1 Yes j
11
i
11
1
11
i
j1
1
1 1 _L_
1f
1
1
1 1947 1 1971
51
lF
li 24 l 23 110.04.71
1 1 Yes |
11
l1
1
11 11
11 f1
J 1
11 1 1 1946 1 1972 1 53
j1 26 l 25 124,12.72
1 Yes f
1S
i1
1
1i
i1
1
11
J
i1
1
11
1
if
1
E
1 1 96 t 1 1973 1 53 l 12
i 05 l 12,06.73
Yes [
I1
i1
1
11
1
i1
J
J!
1
I
1
ff
1
1
1 1946 1 1974 1 53 1 28
i 26 104.09.74
Yes l
l(
1
1
11
F
1
1
1E
1
1
1
i1 ii i1
1 \ 1
|Reactor j cleaner
(Operator
|Smoker
1 polymerisation!
(Maintenance 1 Operator
jmilLwright,
1 pipefitter
EF
J |Operator,
1
|foreman
1
11
FF
1
\Reactor
|Operator,
|cleaner
j foreman,
1 Ivater cooling
|unit
Ff
1 |Reactor
1 |Water cooling
Icleaner
|unlt
11
|Worked (overtime 1 Smoker 1
[Worked lovertime {Non-smoker I j I Worked (overtime |Smoker
I 1 |Worked lovertime |Smoker
1 t Reactor (cleaner
(Maintenance, |millwright
t i Reactor
F |Machine shop
Icleaner 1
(operator and Ipoly unit
i 1 |Reactor
1 |Maintenance
|c leaner
(machine shop
11 F |Furnace op. F J pipefitter 1 (maintenance 1
1
{Worked [overtime | Smoker I 1 1 Worked lovertime | Smoker
F jIn plant | 25 yrsl Smok
1 |Worked lovertlme |Smoker
j________________
Paper hy Dr F DELORME in Annaies d'Anatomie pathologique Paris, 1978 Vol 23 No 2 pp|fl5-M4 claims this case had both a hepatoma and ASL simultaneously.
GENC 0Q8196
Page 3
CANADA Sheet 2
ICI CHEMICALS 6. POLYMERS LIVER Angiosarcoma Casen - (Review Date: i Jan 1988)
DAY - MONTH - YEAR All dates use UK system
WPX/ASL - LANGIOCASES8
1 COUNTRY AND
REFERENCE NO
CANADA 10
1
12
2
NAME OR INITIALS
3 4 151 6 |
_______ JL
L
11
DATE OF
i l FIRST VC | DATE OF
BIRTH
COMPANY | FACTORY | EXPOSURE | DIAGNOSIS
11
JL ii
ii
16.05.15
1 1 1953 i 1976
11
1f
11
11
LC
25.10.13 Gulf
| Shawlnlgan
Dec B5
11
11
11
1\
!1
BC
20.09.14 Gulf
|Shaulnlgan
Mar 62
1J
11
11
6 9 10 ]
_________ _____________ 1
AGE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
61 23 H 00,04.77
72 ? Alive
______________ 67 Mar 82
12 HISTOLOGICAL CONFIRMATION
Yea
Yes
Yes
n 1 14 1
1
15
ESTIMATED
t
EXPOSURE i OCCUPATION I
LEVEL
|
OTHER CAREER HIGHLIGHTS
|Reactor leleaner
|Furnace op. Inalntenance, |packaging
1 18 1
! 1 OTHER | COMMENT!
J j 1
1 1 |Ex-smoker
! 1 i 1 fLetter fron {Dr Fernand |Delorme, |Pathologist
1 1 |Letter froa | Dr Fernand fDelorae, |Pathologist
7
Pngu 4 CAKCUOSLOV AX 1A
ICl CHEMICALS t, POLYMERS LIVER Angiosarcoma Cases - (Review Date: ] Jan 88)
WPX/ASL - LANCI0CASES,9
1 2 34
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OP BIRTH
COMPANY
CZECHOSLOVAK1A
01
28.06.28 State Co
02 06.07.27
5 FACTORY
6
FIRST VC EXPOSURE
DATE OK DIAGNOSIS
a
AGF. AT DIAGNOSIS
9
YEARS OF EXPOSURE TO
DIAGNOSIS
10 1 J l
YEARS OF EXPOSUHE
DATE OF DEATH
12
HISTOLOGICAL CONFIRMATION
! 13 1 14 (
11 i
ESTIMATED
\
EXPOSURE | OCCUPATION |
LEVEL
|
f
15
OTHER CAREER HIGHLIGHTS
Novaky
01,07.57 24.12,73
45
16
16 24.12.73
Yes
Novaky
01,11.50 27.1J.64
37
|Autoclave iClesner
lof 1-4-82
jfrom Prof JA David of | Cent re Ind | Hygiene and (Occ diseases. 1
Autoclave Cleaner
\IARC letter of
f1-4-82 gave Jsonetthat
(altered dates
|for this case. |I have {accepted the
|changes since
| the dates cone |fron Prof
|A David of the | Cent re of \Industrial
(Hygiene and ] Occupational IDlaeases. My
/daces come
lorlginally |from NI0SH.
_L 1
f
1 I i !
J
(
16 COMMENTS
t I i
3*age 5
FRANCE Sheet I
ICI CHEMICALS 6 POLYMERS LIVER Angiosarcoma CaBes - (Review Date: I Jan 88)
WPX/ASL - LANGIOCASES,10
1
t2
13
COUNTRY AND | NAME OR | DATE OF REFERENCE t INITIALS | BIRTH NO
FRANCE
4 COMPANY
f |5
1 1 1 | FACTORY
1 f t 1
6
FIRST VC EXPOSURE
01 |H 02 1 SIH 03 |NAV 04 | MOR 05 1 R
H5.04.24 RP
j 103.06.11
PCUK
! 106.01.20 RP
127.01.27 t
PCOK
129.01.38 PCUK
|Rouse- - 00.01.46
| 11Ion
1
1
1
1 1 |Brlgnoud 06.07.59
1
f
1
l
1
1
(
1 |St Fons
00.00.46
1
1
1
i
1
1
1 |Brlgnoud
19.10.49
1
1
1
1
1
1
1
f |Brlgnoud
18.01.65
1
(
1
1
1
1
1
1
\ 1*
1
1
1
1
71
8
1 1 DATE OF | AGE AT
DIAGNOSIS 1 DIAGNOSIS
l
1 1
1
9
YEARS OF EXPOSURE TO
DIAGNOSIS
18.02.67 \
43
21
1 1
1
1
15.01.75
3 1 f
63
16
3 1
1
1
1
1
\i
1
15.01.75 l
55
29
1
1
1
1
1 1
1 16.01.76 1
49
26
I 3
1
j
3
1 1
1 13.05.76 f
38
11
3
3
1
1 1 1
1
1
f
1 1
I
1
10 i 11 3
i
12
YEARS OF j DATE OF EXPOSURE f DEATH
HISTOLOGICAL CONFIRMATION
ii
1 13 f 14 1
ESTIMATED
1
EXPOSURE | OCCUPATION 1
LEVEL
1
1
15
OTHER CAREER HIGHLIGHTS
i f ! 1 1 |
1 3
16
OTHER COMMENTS
19 319.02.67
Yea
i
12 124.01.75
Yee
(NIOSH no
comment)
j 29 129.06.75
i Yes
j 26 304.01.76
Yes
n 113.05.76
Yes
High High High High High
1
j Aucoclave Iworker and
| |
f |Ref. Ravler e |al Arch. Hal.
Icleaner
3
|Prof. 1 30 n'
119 yrs
|
13 Nov 75
Ip J71-177
1
|2 yrs on
1 jItalian
1 J Ref.
|nononer 110 yrs on
jorigln |
|C Bonne ton et |al "Nouvelle
j polyme r-
|
fpresse
[isatlon
I
Iraedicale"
| J 5 Nov 1977
Ip 7 35
i)
1
f3 }Polyworker |VCH production!Ref. Rety et
110 yrs ss |16 yrs
|al Arch. Mai.
(autoclave |Italian POU 1 Prof. 1 37 n'
Icleaner
[Shepherd,
16 June 77
|Compounding 3 Sawyer, Mason f p 551-555
13 yrs
i
i
tMonomer
J
1
[production jworker 18 yrs
| | I
3
J I
IPVC
|
1
|flltratIon 1
118 yrs
1
|
1 3
1
1 Polyworker 1l)Thoracotomy |Ref. P Coudere
111 yrs
j 9th Feb 1976 let al "Semalne
Icostal
|des hospltaux
1 angiosarcoma 310 Septembre
| 2)Scintigraphy|1976
|found ASL , |Previously had
| 3)Haemorrhage (bone
|froro ASL
[angiosarcoma"
34)Right
[Also
|Hepatectomy J Pilichowski et
j |al "La Nouvell
1 |Presse Medical
3 j7th July 1979
1 |Page 2485
GENC 00819?
Page 6
mtiCK
Sheet 2
IC1 CHEMICALS A POLYMERS LIVER Angiosarcoma Cases - (Review Date: t Jan 1986)
WPX/ASL * LANCIOCASKS,!!
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OP BIRTH
COMPANY
12 13
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
15
J_
16
OTHER
1'
CAREER |
HIGHLIGHTS |
OTHER COMMENTS
i
14.0A.34 PCUK
Brignoud 01.03.58
11.09.76 (NIOSH says
12.09.76)
( 1958-- J960) 2 yrs filtration 10-1l yra polyworker and works lab?
[This nan had 1AOL prior to |AS* Ann. de |Mal. Prof. Uuly *77 fp 645 & 6. [AOL was found |in 1971 five |yrs before | ASL
I______________
26.04.27 01.04.34 Solvay
01.07,50
After death NIOSH says 00.07.76
49
22 02,07.76
Yes
(NIOSH no
comment)
High
Plant forenan In polyaerisation
1972-6 admin section in St Auban
|Died of j septicaemia |Small liver lleslon found |sfter autopsy
23.05.57 03.12.75
42
19
6 yrs packer & autoclave clnr 14 yra autoclave worker
J__________________
1
|Had been |tunnel worker |previously
t I
J_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _
00.10.14
10.0l.4B 26.04.76
63
28
25,12.77
Very High 1946-1966 Lesser Exposure 1966-1976
Polymer
10 yrs in
isation
aulphurlc
operator,
acid factory,
autocleaner, storekeeper &
autoclave
general
maintenance services
|Ope rated 4.76 |for removal of (tumour from fllver and Idled after |second (surgical
(operation for jblllo j bronchial | fistula (Paper by |Dr Rety et al |in Archives de j Ha lades
1 Professionals |Vol 40 No 6 |1979 pages 1741-3.
\
GEW^D08200
y,i7
FRANCE Sheet 1
ICl CHEMICALS 4 POLYMERS LIVER Angiosarcoma Canes - (Review Date: I Jan 1988}
WPX/ASL - LANCIOCASES , 1 2
COUNTRY AND REFERENCE NO
12
13
NAME Oft INITIALS
DATE OF MHTH
24.05.19
15.02.12
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
00.12.56 10.01.70
00.01.41 12.08.78
16.08.14
Sr lgnoud 09.02.49 00.05.79
19.01.31 Solvay
23.09.63 26.06.79
05-04-24
Chios Chlmfe ( Formerly
ftP)
AGE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS 21
30 16
38
TEARS OX EXPOSURE
DATE OF DEATH
10.01.78
13.11.78
27 23.06.79 13 22.08.79
HISTOLOGICAL CONFIRMATION
-L JL f
ESTIMATED |
| OTHER
EXPOSURE | OCCUPATION|
CAREER
LEVEL
f
| HIGHLIGHTS
J_________L
I/
OTHER COMMENTS
High
|Autoclave leleaner
1
I
I 10 yra In Imechanlcal (engineering
I Industry )1946-1956
Died of pulmonary embolism 5 days after surgery
High
I19il-1946 Ipolymer-
1
[isation
(general
|purpose
|worker
|1946-1972
| VCM
leynthesla
i(HC1 &
|Acetylene)
| Foreman
I (agent
|de malt rise)
[ 1972
j retired
I
High |Monomer
I
|
(production |
(and polymer-1
(laatlon
j
[operator
1
jAutocleaner 12 yrs as cycle Cigarette
|2 yrs,
I mechanic.
smoker until
|Au to-
110 yra aa
1974. Ill a
loperator
(enameller In of 1977 due .
19 yrs,
(sanitary ware Oesophageal
|Copolymera Jmanufacture
|4 yra
I
varices. Surgical
intervention
l 25.05.79
right
I lepatectomy)
Very High (1943-1975 [1975-1979
1943-1975 (All types of(maintenance
and
I jobs on
(work
intermitt-(manufacture I
ently
|& maintenance
1975-1979 |1n VCM Poly I
_______ | Process
|
GENC 008201
Page 8
FRANCE SheeL 4
ICI CHEMICALS 4 POLYMERS LIVER Aiagl nun rt'omji Cases - (Review Date: I Jail 1988}
WPX/ASL - UHGtOCASKS.n
COUNTRY AND REFERENCE NO
NAME OR \ DATE 0? INITIALS | BIRTH
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF YEARS OF EXPOSURE TO EXPOSURE
DIAGNOSIS '
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
J3
I I
ESTIMATED |
EXPOSURE | OCCUPATION
LEVEL |
15
OTHER CAREER HIGHLIGHTS
16
.OTHER COMMENTS
J1
1(
1
\1
France
t
11
11
1
J
1
1(
J
lf l1
r j
ILeft Hepatectc* J1983
15 | DEP l 1 [ 1 i 1
16 GIM
103.01 37 | Chloe
| Sc Fona
1
| Chlale
i
1 | (formerly 1
i
i kp)
1
11
1
11
1
1!
l
1 07 07.55 128,09,82
11
11 1( 1l !1 1\
J
i 1 1 1 1 1
13,07.22
Chloe Chicle (.Formerly
RP)
17.10.41 05.01.83
45 61
1 27
J 27 [Alive
1
11
1
l1
1
JJ
1
i
11
1
I1
[
i
_ _ _ L-
1
1
38
Yea
22,02.23
Chloe Chlale (Formerly
RP)
17.06.48 03.04.83
60
34
03.04.83
1Hlgh-20 yr lAutoclave |
|Mode rate Icleaner
|
J 7 yrs
J1955-1962 |
1 lautoclave J
1 loperator |
1 J 1962-1982 |
1 JL. _
f
Hlgh-33 yrs|Polynerisat-
Hoderate- lion Process
Low - 5 yrafHan
1
|Maintenance
|Uorker
i
|Health A
{Safety Agent
______________ I________________
I
High -
j Autoclave
Other sectors
23 yrs
|Cleaner
of St Fons
11948-1971
Factory 1971-
f 1978
1
|J C Contassot
|S 10 1983 1 1 1 f
| Retired 1 Jan 1979. |J C Contassot I Letters of 15 10 1983 and 125 7 84.
1
J
1 I I
iRetired 101.01.79 |3 C Contassot J Letter of 15 10 1983
I 1
14.07.42 Solvay
09.09.63 21.03.84
21.03.64
High- !2 yrs[Autoclave
Low - 9 yrsj Cleaner
1 ! 1
f
_L !
J09.03.84 I Right IHepatectoray 105.05.84J24.09.84 Icheaotherapy |for lunglmeta&taals : [partial ]remission. |08,84 - liver [recurrence. J10,84 - lung: (evolution of (the disease
j______________
GENC 008202
Page 9
FRANCK Sheet 5
ICI CHEMICALS & POLYMERS - LIVER Angloaa rtniM CaHea - (Review Date: I Jan I98H)
WPX/ASL - LANGIOCASES , 1 4
l
COUNTRY AND REFERENCE NO
FRANCE 19
20
1 21 r
i i i i i i i 22 1 1 I 1 J 1 1
1 2 13
4
1 1 NAME OR | DATE OF
INITIALS | BIRTH
COMPANY
1
J 1
1
1i MAZ 115.12.32 Atoches
1 ! t 1 1 BR 102.03.23 Atochen
1 l 1 1
Ii !5i6
J _L 1 1 FIRST VC | FACTORY EXPOSURE
7
DATE OF DIAGNOSIS
t 1 _L 1i li
i
1 1 Brignoud
07.04.59 26.10.84
1 1
1
1
t | Brignoud
1 1
i
1951
i 27.12.65
1
1
8| AGE AT | DIAGNOSIS |
52 |
63 | I
j!j|!!!!!I\\ji
11
11
1
1
Pa 101.10 40 | RP
| SEP
| 1959 I 03.06.86 1 45
1
|Montlucon|
1
1
11
11
1
1
11
11
1
J
1i
11
1
1J
11
1
1
11
11
1
1
11
11
1
1
t1
11
1
1
i1
t
l1
AL |L3.08.2B | At ochea | St Auban 01.09 58 I 05.11*87 1 59
11
1
11
1l
1
11
11
1
11
1l
11
11
1
11
t1
l
1f
f 9 10 1 11 12
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF l DATE OF EXPOSURE \ DEATH
HISTOLOGICAL CONFIRMATION
25
25 106.11.85
Yea
34
22 I26.J2.85
Yea
.X
1 11
1
27 1 4 128.06.86 J Yes 1
1 [1
1
1 11
1
1 11
1
l (l
l
1 11
1 11
1 11
1--
1
\
1 11
)
29
1 26 |Alive 1
Yea
1
1 11 1 11
1 1
1 11
1
1 \1
1
1 11
1
1 11
f
11
13 1
14 j
15
1
16
11
11
ESTIMATED i
1
EXPOSURE j OCCUPATION |
LEVEL 1
1
11
1 (Autoclave
1 \
High
loperator and!
Icleaner
|
OTHER CAREER HIGHLIGHTS
t 1 OTHER I COMMENTS
! 1 |Myocardlal
|infarction J1980.Corona Ibypass 1981
1J
ILetter froo
1J
|Dr Contasso
j1
15.4.86
High
11
|Autoclave |In other parts[Portal
loperator and|of factory
[fibrosis fr
(cleaner 1
|since 1946 l
126.04.74. [illness was
1J
Idiagnosed a
11
Fpresuaably
Iwork relate
|on 20.04.74
ILetter froo
|Dr Contasso'
105.04.86
High
High 1958-70 Low 1970-84
11 lAutoclesner Maintenance
|4 years
| wo rJeer
t1 11
(1
11 1t
1
!
1 |12 years
lAutoclave
|worker.
1
J
! |
|
f
f1 |)4 years in j
(Control Rood|
11
t jHepatic tesi (May 84 nornu
|Hepatic teal
|May 86 show*
labnornalitii
ILetter fron
| Dr Barrat
|18.07.06.
_l_______________ 1 ILetter froo |Dr Contasaoc |Atochen 12.L2.87
1 1 1 i i
\
i
f i I j
08203
Pa*e
GERMANY Sheet 2
ICf Cfit-MICALS 6 POLYMERS LIVER Angf onarcocnu Cases - (Review [lute: l Jan 1988)
WPX/ASL - LANGIOCASES,16
1 J1
1 1 COUNTRY AND | REFERENCE 1 NO j
1
GERMANY
|
t 2|
1 1 NAME OR j INITIALS | 1
1 1
3 t
DATE OF BIRTH
!
1 4 i5
_L i
COMPANY
i t FACTORY i
_L l
l
61 7
FIRST VC | DATE OF EXPOSURE 1 DIAGNOSIS
05 1
1 (NIOSH gives| as Case 06) )
1 1 1 f J 1 1 1 1 1 \ 1 1 1 1 l 06 |
J (NIOSH gives! as Case 05) j
L 1 07 f 1 1 1 ( ! 1 1 J f J f 08 | I 1 1 t
!00.00*36 J 1 1 \ 1 1 1 l j 1 1i 1 1 1 1 1 1 1 t ]00.DO.32
1i 1 1 1 100.00.26
l 1 1 ( 1 t
11
7 8
f 100.00.17
4
l1 I
1 1
02.04*60 ) 10.12,73
1
7 16.12.62 j 00.00.75
-L 6 15,04.54 j 12.11.75
1 1
1 1 1 1 (4 J 1 t 1
19.07.54 i 06.04.75
a AGE AT DIAGNOSIS
38
43 49
58
l 9 1 10 1 N
11
1
12 i 13 1 14 |
i
11
1
1J
|
YEARS OF 1 YEARS OF 1 DATE OF HISTOLOGICAL I ESTIMATED 1
t
EXPOSURE TO | EXPOSURE 1 DEATH
CONFIRMATION 1 EXPOSURE 1 OCCUPATION |
DIAGNOSIS
1 LEVEL 1
1
i
f1
F
11 1
1F 1
13 1 05 116,12.74 |Yea {NIOSH) |
| BG Chemle |
1
Isays
|
1 1"chemistry |
1 1 laboratorlan|
1
|in the
|
1
(Techno-
|
1^
(
Jlogical
j
\
|Research
|
1 [Department" |
-1
|(NIOSH says j
1 (assistant |
i
Ifactory
|
1
fchemist
|
1 Iwbich may be(
1
1 wrong
(
1 11 ranslaclon)|
]1
1
1(
j
11
1
13 t 12 109.01.75
1 Yes |
1I |PVC - Mami- |
1
Ifacture
|
1 (Shift Leader|
11
1
11
1
21 1 21 113.11.75 ((NIOSH
i Yes |
1
11 (PVC Manu- | Ifacture and J
| says 12)
J
I a11 work
|
1 Jincl auto- [
1
(cleaning
J
1
112 yrs
|
l 1(1954-66) [
1 1 Foreman Tech]
f JDev 8 yrs (
1 (0967-1975) I
11
F
20 1 20 125,12.75
1I
1
Yea | ? 1 Polyworker 1
11
1
11
F
J1
J
11
1
15 1 16 F
OTHER CAREER HICHLIGHTS
'| |
1
OTHER COMMENTS
|Confirmed
1 (Reported un<
J non-polymer| lest ion [workers in jNIOSH list c 131.3.77 and ) 1.78. I don Ithink this 1 |a correct fclasslf lcatl (by NIOSH. T I me n may have
[been Involve |in VCM 1polymerlaati |in pilot pla |or In main Iplant.
1 J
1 1
|
1 1
I 1 1 J 1 |
1 1 1
?
1 (
J
GENC 008205
Page
CERKANY Sheet 3
12
COUNTRY AND REFERENCE NO
HAKE OS INITIALS
DATE OF BIRTH
COMPANY
00.00.34
10 {NIOSH gives
as Case 11)
00.00.36
11 (N10SH gives
as Case 10)
00.00.29 00.00.38
1C1 CHEMICALS 4 POLYMERS LIVER Angiosarcoma Cases - (Review Date: 1 Jan 1988)
WX/ASL - LANGI0CASES.17
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
20.02.61 16.06.76
00.01.77 10.10.55 28.06.77 00.00.61 00.10.77
AGE AT DIAGNOSIS
47
YEARS OF EXPOSURE TO
DIAGNOSIS
15
12 13
YEARS OF EXPOSURE
DATE OF DEATH
13 24.03.78
HISTOLOGICAL CONF1RHATION
I
ESTIMATED ( EXPOSURE | OCCUPATION
LEVEL |
__________ I___________
t
High
peaks
j12 yrs poly(worker incl |11% auto|clave Icleanlng |Control room M yr
l
07.03, 77
1
High peaks jlO yrs poly4worker iticl
1171 autofclave (cleaning
I
1
22 28.06,77 07,10.77
High
|3 yrs auto
clave
Icleaner
\19 yrs |filter
loperator
J___________ I
IPVC Manu| facture (Autoclave |worker for f6 yra
I
I
OTHER CAREER HIGHLIGHTS
OTHER COKHENTS
10/ 78 Confirmed Average exposure fir 9 yrs 150 pp occ 1000 pp Next 3 yrs a 75 ppm. Las yr av 35 ppm
Average exposure fir 9 yra 150 ppt occ 1000 ppr Last yr av 7 5 ppm. CUH letter of 21.04.78
GtNC 008206
Rage
13
GERMANY Sheet 4
1
COUNTRY AND REFERENCE NO
2
NAME OR INITIALS
si
.. ... i DATE OF |
BIRTH i
s COMPANY
GERHAHY 13
00.00.14 |
7
L 14
15 (NIOSH gives! this as Case 13)
16
00.00.29 |
8
100.00.23 |
4
[Cl CIIKMI CALS & POLYMERS LIVER Angiosarcoma Cases - (Review Date:
Jan 1986)
WPX/ASL - LANG 10CASES, 1 6
5 FACTORY
FIRST VC EXPOSURE
7
DATE OF DIAGNOSIS
6
ACE AT DIAGNOSIS
9
YEARS OF EXPOSURE TO
DIAGNOSIS
10
YEARS OF EXPOSURE
11
12
1 DATE OP | HISTOLOGICAL
DEATH j CONFIRMATION
1 1
13 1 J 4
ESTIMATED EXPOSURE | OCCUPATION
LEVEL
1
7 00.00.60 08.04.76
63
18
14 19.05,78 1 Yes
I
1 1
!
_______________
\ |Not an
1 Angiosarcoma | In his let ter '' |of 21 12 61, IMr Frledel Isaldthls was fa "Piattenepl1Chelkarsinom | Der
|Spelserohre" j(a carcinoma |of the (oesophagus) |not attrlbutfable to VCK 6 /not recognised |as an IndustIrial disease
1
8 19.10.53 09.10.78
49
25
25 23.10.78 j Yes
1 |
1
f J
/Autoclave /cleaner and Iworker* 1 Drier loperator. /Later shift | leader
1
1
4 10.01.55 07.08.78
55
23
20 07.08.78 1 Yes
High | Autoclave
(Lelbach
|ASL and
|worker till
suspected
|Hepatocellular
11964.
A5L at Feb 1975 laparotomy)
J Carcinoma |
[Leader and Inaster
t j
/ 1
1 1 1
--j
fg"
0TI1ER
|
OTHER
CAREER |
COMMENT:
HIGHLIGHTS I
____________ t_______ 1
i
IF U Best lletter of J30th June 1 (enclosing cl | from I Mr H P Frle _______________ | of BG Cheal IF hT Best lletter of 130th June 1 (enclosing d | from |H P Frledel l BG Cheale fwlthdrawing (this esse
I
I 1
I I
J_______________ I Anglosarconu 1confirmed 109/79. Soa< /detail of t? 1 A also casef
19, 13, 15, I j & 17 given 1 |NRtf Report f f 1976 1 Angiosarcoma I confirmed, Ifull details |of Illness (since March [1973 given 1 INRV Med insp |Rep for 1978 | Different /details give jin "VC (Associated |Disease" by jLelbach and 1Mareteller
1(1981) P71.
G 008207
Page
ck many
Sheet 5
COUNTRY AND REFERENCE. NO
NAME OR INITIALS
DATE OF BIRTH
GERMANY
17 (NIOSK gives as Case 15)
00,00.37
00.00.13 19 00.00.25
00.00.15
00.00.13
00.00.21
ICI CHEHLCALS f, POLYMERS
LIVER Angiosarcoma Cae
(Review Date: 1 Jan 1988)
WPX/ASL - LANCIOCASES.19
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
01,11,61 14.08.78
00.00.55 "25.12779 18.10.54 00.08.79
14.02.61 00.04.80
01,01.62
00.09.79 pronounced : linical liver symtoms )
15.10.61 26.08.80
ACE AT DIAGNOSIS
41
66
YEARS OF EXPOSURE TO
DIAGNOSIS
24 25
YEARS OK EXPOSURE
DATE OF l HISTOLOGICAL DEATH [ CONFIRMATION
26.08.78 [
i
25,12.79
22.02.60 |
Yes
IMetaataaleig
| ASL
I
_L
9.10.80 f
Yes
[Haemsagio j Endothelioma |of liver with
|Hetastases
1
13
9.06.80 |
Yes
jHsemsnglo j Endothelloma
|of liver with
[Metastases
__________ J___________
06,12.81 f
Yes
[Metastaslng j ASL
1____________
n
ESTIMATED EXPOSURE
LEVEL
u
OCCUPATION
j
OTHER
f
CAREER
|
H1CHLIGHTS |
_________ !
OTHER COKHENTS
High
Autoclave worker
High
Autoclave Worker
tutocleve Worker
High
Autoclave Worker
f
I
| Angiosarcoeu Iconf i raad. IAnnual repoi Jof the North |Rhine IVestphBlla [Medical 1Inspectorate I for 1978 Ipages 347-37 |gives full Idetalls. Vin Ichloride [disease (diagnosed 102-02-73. J Oesophageal Ivarlces. [Radiological [confirmed ac loeteolysla.
i I Dr Beeche lletter of 113-04-82 to I Dr W C F Adair
I ________
|Dr Besche [letter of [13-04-82 to |Dr W G F Adas
High High
Autoclsve Worker and worked In drying shop
I Dr Besche lletter of
I 13-04-82 to I Dr W C F Adai
Autoclave torleer
Chargehand, subsequently toreman
I___________
|Dr Besche
lletter of |13-04-82 to | Dr W G F Ada
I'dge
IS
IU CHtMlCAl.S 4 HOI.YMhHS
WPX/ASL - LANGLOCASES,20
GERMANY SFuui t 6
LIVER Aug I osart mi.< Cases ( Rev Date: I Jan 19BH)
1
13
4
5F
6
COUNTRY AND
REFERENCE
NO
GERMANY 23
1
f
t
1 1 1
1 24 1
l
l
1 23
26
27 1
t
NAME OA | DATE OF
t FIRST VC
INITIALS | BIRTH |C0HPANY| FACTORY 1 EXPOSURE
11 \1
1 100.00,27
6
8 \ 1935
I
1 |
1
t 100.00.28
1 l
! 100.00,23 1 l t 1 100.00.22
l 1 1 1 j00.00.28
1
\
8 8
2
4
fl f 1969
8 1 I960 2 1 1933 4 1 1955
28
121.11.20
7
| 01.10.60
|
|1
J1
11
1
11
11
11
11
11
!1
1
11
1
!1
1
29
100,00.22 1 2
1 1962
11
1
11
1
30
100.00.17 1 4
4 1 1951
11
1
11
1
3)
100.00.23 1 8
8 1 1953
11
1
11
1
32
100.00.30 | 8
a 1 1955
11
1
11 11
1
7 DATE OF DIAGNOSIS 26.03.79
11.30.82 26.09.81 14.06.76 18.01.83 11,08.85
15.02.83 07.01.80 30,06.85 00.04.85
8 ACE AT DIAGNOSIS
52
54 38 54 55 61
61 62 61 55
\l
9
10 1 1 1
12
11 i 1 14 |
YEARS OF EXPOSURE TO
DIAGNOSIS
1 | YEARS OF | DATE OF EXPOSURE | DEATH
F 1
J1
1
HISTO- |
1
1
LOGICAL | ESTIMATED \
1
CONFIRM- F EXPOSURE | OCCUPATION |
AT10N E LEVEL 1
I
11 1
J
11
1
24
21 129.09,81
Yes 1
High | Chemistry |
1
l( '300 pirn) | Worker
\
1
11
1
1
1\
1
1
11
1
E j1 1
1
|\
1
13
12 |28.05.83
Yew t
High [Autoclave [
J
l( >300 ppm) {Cleaner
|
1
11
1
1
11
1
21
13 | 14.01.83
Yes I
High |Polyclave |
\ 1 |Worker and |
1 1 |AutocLave |
1
1
| Cleaner
|
1
I1
1
22
22 122.11.82
Yes l
High IPolyworker j
1
11
1
1
i1
1
1 i1 E
1 i1 1
28
18 102.03.84
Yes 1
High |Autoclave |
1 1 |Cleaner tlll|
1
1
11972
1
1 1 JL
25
25 125.08.85
Yea 1
High {ProcesB
\
1 1 |worker 1947-1
1 1 184 (01.10.60{
1 1 1-31,03.84 |
1 f |PVC prodoct-l
1
i
Hon,
\
1
i
(agitator
J
1
i
(area).
|
1
i1
1
1
\1
1
1
i1
1
1 i1j
1 iF1
21
19 ( 15.02.84
Yes i
High iChemistry |
1
i
Iworker
l
1
i1
1
29
23 125.05.83
Yes i
High | Poly worker |
1 i IShift leaderl
1 32 1 20 (Alive
at i ? JAutoclave |
1
Icteaner
|
1 30 21 |A1Ive
F1
1
1 ? | Polyworker |
l 1 |An t oc1ave |
111
Icleaner
|
1 1 J______________ L
15
OTHER CAREER HIGHLIGHTS
1 16 1
!
1 1 OTHER COMMENTS
1 1 1 j Primary hepatocellar |caret noma; proliferation of the Islnuslodal cells with |sinusoidal ectaela. IFrledel letter 23.12,86
i |Prof Eder (Munich) 1 letter 22.06,83. IFrledel letter 19.04,85
i |Prof Selmalr (Munich) fletter 22.08,63. IFrledel letter 19.04.85 1
I 1 Chronic hepatitis, |angiomatoala , alnusoida lectaala. Friedel lette 123.12.86.
1 j Lelbach, |Friedel letter 119,04,85
lArmtal VCM screening
(24.04.85: no complaint. [no abnormality detected |J 970 two-thirda Igastrectomy for ulcers. 1 1971 Coronary throaboal. 13 983 Femoral flmplantatIon 11964 Pulmonary embolism land pleuropneumonia. |Landers letters 18.09.8 land 04.02.87.
r J KsemanglosArkoma. IFrledel letter 23,12.86.
| Haetnangiosarkoma. IFrledel letter 23.12,86.
t \ Haemsngiosarkoma. IFrledel letter 23,12.86.
1 | Haemanglosarkoma. IFrledel letter 23.12,86.
1 J
W\, ' t J Al
Ifi
> i l ! ?ii 11 r i /.i . i '.'I iMi
i :vj k Any! i us.it i ! > immi
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`"I P ifi"3 H Y AND Ml I'j lit N( K NO
name ok
! n r ] i aj s
DATE OK HIKTH
l, l ;n' n ] < i si l
SI||I|.J VriH-"l .iry
I ) ' l )
lS.Ob.lt
Ml ra V t* n i c
FIRST VC f-.XFOSlIKh
IJATP OF O lAt.NDS I '
AOh A'l
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IVATK :!> Oh A I H
I
lilStOLOLlt'Al ( <JNH KMA Tl ON
h STIMA THE |
KXhKSOKK |
LKVM
|
__ ]
t
OtClJFA I'tHiS
IFVC Hag I ext ruder
0 rilt.K CAREER HlOHUuHTS
OTHER COM MIS NTS
lJrtmary turm may have be* per I on rd Iedh Not homo geneous wltl other rases.
Montedison Porto Fia rghera
00.00.57
Solvay
10.07.75
1 11 11 1I1I
04 l t FB j
f1 1 1 1
j
1 1
l|20.07.37 1 1 3
\
1 1 1 1 1
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ll
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1
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1i
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00.04.59 | 00.01.8]
1111
f
1
43
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11
11
31
fJ
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V e M.iltvo.1 Med dl l.avoto b_6 i^^j, I ^ ? h . nniher details In letLet fron, Ot Montesai'ii nt [Afo' no April I s c |482.
\l-.j S. . Mi it Mill and KondtneJl.s 1 u Ai La Uniting La V j S L |9RlJ piges 1 'i - 44.
Yes Yes
IFolywo rker
3
high
f lAutocteaner
1972-5 did
18 yrs (1953-
a variety of
lb ]) AutocSav J bs
1 (operator
(Including!
1 |12 1 91yrb ( > l - FVC packing, j
1 72| )
|
,
1 1!
12 11| yrs -
yr-
J Never cleanest
1 1l Very Kign Momime r
autoct aves.
f
11 5 1 1 0 1yrs 1 120 1Medium
loperatuc yrs -
|See paper hy ICH APPIN et lal Med Lavoro
* j hon-Bm oke r.
Consumed
1 6 982 111I Autoclave fVol (F )
tt le
1 1 555-56 3 3m yrs 1 0\ Low
I o pe ra a r &
pp
o t he r duties!
I a ] rohn . | A L.
IS*.
1 11 6 1n s u pens-
1 |ion polyme r1 |isatlon.
1 1
!
1 1 1
F
1| .Me J urn-* 1 High 3 \1 1
{Area Foreman!
f t n same he pt|
1 97 5| since
.
1
F1
9 7 975| Bag extruder]
| l f> - ]
3| Co mine ro i a 9I he fit ] ?ti-
\ i*m j
1
1 1 11
i
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1 2 Aug 1983
l
1
J
GENC 008210
I'.IK'
II
I I AI Y
\ MJ CAI S ft I'OLYKh KS
: rvi.l' Ai !>!. I' ............. i
iKfoU'w ; J.ili-: I J ii n ] 'J MU >
WPK/ASL - lANG[OOASK 1
rciUNIKY AND KK K> XENCE No
NAME OR INITIALS
DATE OF BIRTH
! TA[ V
FIRST VC EXPOSURE
DATE (it D]AG NOS J S
ACE A r U 3 AGNl LS i S
YhARS OK EXPOS (IKE
U[ACNOS[S
YEARS OK EXPOSURE
DATE OK DEATH
H ! S fOLO<, 3 CA3 ESTIMATED CONK[KMA 1 ON EXPOSURE OCCUPAT ] ON
LEVEL
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
Ho nt edition. Porto Ha rghe ra, Venice
HiRh 1960-7l Kedt um 1971-74 Law
1975>-H5
PVC mn iih f ac t u re U years as Au c oc ave c1eaner 1960-71, 14 years Jr. Control Room
1971-85
Letters t rom Dr Cfilozzlni, 22.09.87 a nd J 1.0 I , 8 H
GENC 008211
I Ar'
III i II II
i Ml I"
LI v' K ft.i^3 n ,i r, n '.im-s - iK'uK-u IldL-
I Ljm VgP)
WJJX/AM, lam; I: KJA SKLS , 2 i
1 1 Mils 1 i'i AND
Hi H Hh NO' vn
JAPAN II 1
02
Ul
1 12 1 1 | NAMK OK | INITIALS
E 1 1 1 1 | 1 urno | 1 fMort
! 1 1 1 1 1 1 1 1 1 l 1 sr i 1 1 1 1 1 EYS l l i l l
i r3 t t | DATE-. OF1 | Ji I K fli
1 1 1 1 1 |0 1 .08.22 1 1 1 1 1 t \ 1 1 1 1 1 |02.08.19
1 1 1 1 l
i01 .09. JfJ 1 1 1 1
1
1 4 15
1l
11
El
I COMPANY | h ACTO H.Y
11
11
1
I1 1I
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f Nagoya
|Toatsu
1
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11
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11
11
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11
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|Toa t su
1
11
11
11
11
6 h'JKST VO KX 1*080 HK 00.04.51
00. 11.58 Uo.o7.f,S
7
DA IK (JK I) 1 AO NOS 1 9
* 24.10,75
HI .08.7 f>
2h.06.45
1 1 1 1
1
1
14
1
1
AO A 1
J Yf AKS (jK
111 ALNOS 1 S t 1 XPOSIJKK TO
J J J J A( i N 0 S1S
1i
11
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11
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1
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* 51
22
1I 1 1
1 11 |24. If). 75
Yes
1
1 I | I'VE, As sol
ii ii ii ii 111 yra a n t <>-1
1
Isays not
jc lave
|
f
| k n cvw n.
(c leaner
|
1
| * Japan
E t 964 -
|
1
111 me s
Sassigneii to 1
1
| 1 mil l at ed | ii 11 f ere nr
|
1 jon 25 . 10.75|work si nee |
1
Jexposures |had lit
e
1
Joften at
lliealth
|
11
| 3000 p pm up |
|
1
ten 1974
1
E
11
11 1
11
11
1
17
17 | ii i io. im. it.
Yi-s
| Mi:, 1 k in,util i In pul v'4' r - J
1i
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1i
1
IJ nclud E ng
]
ft
1 j ant oe1 awe 1
fi
1
Jcleaning
1
_L_____________ L________________ 1______________ _L
ir
54
2 J I 5 | I*..09.4 5
Yas
1i
11
1
High
15 yea rs
i 1 |
11
1
|Autoclave
1
t
1
Ecleaner
|
S1
11
1
Er
11
f
1i
11
1
5
OUEl'.K CAKKJ'.K HIOHUOHTS
1 r i6
i i i on tut i COMMhNI'S
1 1 1 1 1 | J a pa n '[ 1 ire h 1 2 5.ID.7 5 4 IJapanese PV> j Assoc 1 e11ei |of 31.01.78 1 3lL t 1 .87 i
1 1
1
1 l l hi pn m-Jiu: 11V
| Ah h tit i n l Ion |letters of 111.01.78 4 I Ml. 1 5 .87
1 1 | J.e 11 e r f rorr
|D r Na kamu ra,
IJapanese PV>' | As soc 1 a t i or. 110.11.87
F
* In his letter of 1st April 1982, Dr Montesano of IAKC save Japanese Ministry of j.abour give
Mete of diagnosis - 21-08-74 Age of diagnosis - 52 Years of exposure - 22
GENC 008212
NokUAY
I 1 I ,11 Ml i M
'i Ml I"
LiVtK AvI is.inuw lases - ( 10* view Pate. i Jan ISHHi
WI'X/AM - L.AN<. E0( ASE5 ,
1 i|
l i aIN l R i AMJ |
REFERENCE | NO |
NORWAY
1 1 |
1 2i
1 1 NWr. OK | INITIALS | 1 1 1 1
3
DAI K Oh BIRTH
1 1 1
1 1 i
4 COMPANY
11
I5
6
1 f
1 | FACTORY
FIRS! VC EXPOSURE
l 1 1
7
OAT r Oh 0 1 AO NOS l -i
01 | AH
1 1 1 1 1 1 l 1 1 1 l 1 1 1
|23.1 2.15
l 1 1 i t I i 1 1 1 1 1 1 i
Norsk Hydro
J Heroya 1 1
1 J 1 1 1 1 1 1 1 1 1
00.03.50 21.12.71
1 1 !
" AGE AT U1 AO NOS IS
56
1 i1
9 f 10 1 I J J
12
t 11
1 1l
YI-.AKS OK | YEARS OK i UATK OK HISTOLOGICAL
EXPOSURE TO ( EXPOSURE I DEATH
CONFIRMATION
DIAGNOSIS j
1
11
ll
11
22 | 2 l 104,01.72
1J 11 1f 11 11 11 11 1l 11 11 \1 11 1J 11
J_ I I I i ! f
Yes
\I 1
K
ESTIMATED EXPOSURE | OCCUPATION
LEVEL
High
| Foreman & |Autoclave J su pe rvls n r
)5
OTHER CAREER HIGHLIGHTS
I 1 lr>
1 \ | OTHER | COMMENT
1 I 1 1 j I Confirmed 1 |Or ThlIs|Evansen ot | AC APME Kti J9 June 1971 f Mr P Ka ngm | slated tluil I had been a {member of i
| start-up it | VCH & PVC w {made In Ram 1 hu 1 t cl t ng . |VCH was mad |f rom acet ys
008213
M3800 3N39
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UPK/ASL - LANGUK ASKS t 2b
COUNTRY AND REFERENCE MO
2
NAME Oft INITIALS
31
DATE OF BIRTH
l 1 |
1
f
4 COMPANY
15 1 1 l 1 FACTORY 1
6
FIRST VC EXPOSURE
7
DATE OF DIAGNOSIS
8
AGE At DIAGNOSIS
9
YEARS OF EXPOSURE TO
DIAGNOSIS
10
YEARS OF EXPOSUKE
1l 1
12
1
1 DATE OF | HISTOLOGICAL
DEATH | CONFIRMATION
1
13 1 >4 1
J
ESTIMATED
1 1
EXPOSURE | 0CCUFA]ION |
LEVEL I
|
15
OTHER CAREER HIGHLIGHTS
{ j 1 1 | |
16
OTHER COMMEN'J
UK
01 WJ
20.04.01 ICI
HIJIhouae 04.04.44 03. 12.72
71
28
22 0 4.12.72
Yes
500 ppm 1944-7 VCM
( Fox 6
< Fox 8
1947-8 Drier
Collier
f'ol lO-r
1948-61
paper
paper
Autoo 1ave
23.12.72)
says
ope rator
23.17.72)
1961-66
Drier
Lee a net Els r Lancer 29-06074 pages 1316-
Dubious fabrlcat lor. case
23.06.20
00,06,79
High
Au t oc 1ave c teane r
Exp osu re 1imlted to 2.66 - 9.69
hied 1 urnhigh
54-5 Bagging Plant 55-6 Drier Plant 56-58 Autoclave worker 58-61 Chargehand Drier Plant 61-72 Foreman C 2/3 Plant
Pre-war fish packer 1939-45 army veh tc 1 e maintenance 1945-54 fish packer
11
SENC 008215
I'.m-
MK Sheet 2
//
COUNTRY AND REFERENCE NO
05
NAME OR INITIALS
DATE OF BIRTH
10.03.M
19 31
26.04.20
08 | WTM
1 1 1 3 1 1 1 l 1 1 1 1 J 1 1 1 1 1 1 I 1
1 08.05.24 1 BP 11 11 1J 1f 11 ll 11 11 11 11 13 11 11 r1 i1 i1 i1 !l
1s
11 11 11
Be rry
Barry
Barry
| Barry i j 1 1 1 \ 1 1 1 I 1 1 J I 1 1 j 1 1 1 1 1
in Minn \i i. mi ymi m LJVFH Angiosarcona Casts - (Review Date: I Ja-i I 9H8)
WPX/ASL - LANG IOCA.SE.S , 2 7
FIRST VC EXPOSURE
DATE OF DIAGNOS I S
oa*oi.51 00.10.7 9
1962
09.ni.8f)
00,00.80
AGE AT 01 AC NOS[S
48/9
YEARS OF
EXPOSURE TO DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
19.1 1.79
11.06.80
HISTOLOCICAL CONFIRMATION
n
estimated I EXPOSURE | OCCUPATION
LEVEL | I 1 3951-52 |Polycleaner I1962-55 I Latex I 19 5 5-ftO I Poly M ixir 11960-64 |Voly I Cti a rg eha nd I 1964-70 I CHargi 'HI I MfH-UI I m 1 I9?n-U I Urier I operator I________ J 7 yrs ] Po 1 y Fluor I Op e r e t o r 35 yrs I Greaser on j Poly Floor j Polycleaner I3961-5 ) Recovery I 1965-197]
]5
OTHER CAREER HIGHLIGHTS
OTHER COMMENT:
1 19.09 50 E 27.! 1.8] 11 11 11 11 fi \1 11 1] 1J 1F 11 11 I1 11 11 11
\ \1 11
t 11 11
1 1 1 1 J 1 3 1 1 1 1 1 1 l F 1
1 1 1 1 1
57
1 1
; l 1 I \ 1
31
3 24 t 25 12.81 | 1 t1 ! 11 1 ll 1 11 1 i1 1 FF F 11 l 11 1 11 1 11 F 11 1 11 1 11 1 FF 1 1l 1 11 1 3i
1i 1 1i 1 15
\f 11
| 1950-195B E 500 ppo |1968-1974 1 200 ppm 1 1 1 1 3 i \ 1 1 ! 1 1 i f 1 J I 1 1
f | 19 50-51
11918-1948
f
1 A u c oclave fMo tor Mechanicf
loperator
J 1 948-1950
I
31951-3957 lOperator on f
3 Ch a rgeioan SAcetylene
|
I aucoclave | Production
i
I bui ldt ng
|Plant
|
1 1957-1974 fShi ft 1 supervisor 1 aut oclave Ibuilding 1 Never 1 cleaned lantocl aves
1 1 1 1 1 1 f 1
1 1 E I 1 i 1 i
Ibut
1
I supervlsnr's E
Ij oh entailed 1
1 ente rt ng
1
i d u t r m ] i,s 1
T t ri j us pier t 1
| t Ftem
1
l1
1 1 l 1 1 f 1 1
GENC 008216
,1m i r 1
J
\2
l3
COUNTRY AND KEPFKENOK NU
UK 09
| NAME OR | INITIALS
J EICP
1 DATE OF [ BIRTH
107.03-25
10 ICJT
tOii. 04. 47
1 | G LP
108.05,28
1 2 J JT
124.0].37
4 COMPANY BP
15 l 1 | FACTORY 1 1 1 Barry 1 1 1 j \ \
6 FIRST VC EXPOSURE
15,02.50
1
1
1
1
1
BP
J Bar ry
27.04.66
\
l
1
\ 1
1
1
1 1
1
\
BP
| Barry
19.12.65
1
1
1
1
1
1
1 1
1 1
1 1
1
\ I C [ | H1 ] house 16.09.57
l 1
1
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1 \
;
\
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r r vi r aji h i M ............. 1 1 1
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71
1 DATE OF |
DIAGNOSIS |
1
f 02.03.83 |
1 1
\ 1 1 1
l f
01 05 84
1 1 1 f |
1 1 1 1 1 1 r
02.06.85
I i i i 1
i 1
03,06.66
1 J 1 1 1 1 1 3 1 1 1 1 |
1 1 1 1 1 1 1 1
fi ACE AT 0 J AC NON IS
58
37
57
48 <
91
YEARS OF EXPOSURE 30
DIAGNOSIS
33
1 1 \
1 1
1
18
L9
3 2d 1
1
i 1 1 1 1
JO YEARS OF EXPOSURE
29
4.2
16
28
11 1
1 DATE 0F |
DEATH |
1 1 24.02,83 1
1 1 1 1 1 1 1 1 J 1 l 1 16.05.84 ]
1 1 1 1 1 1 1 J 1 \ 1 02.06.85 |
J 1 1 \ 1 1 J 1 1 1 1 1 1 I 06.12.85 |
1 1 J 1 1 1 I
1
12 J n 1 U E
1
Jlf 5TOLOCICA1, 1 ESTIMATED
|
CONE1KMATION 1 EXPOSURE ! OCCUPATION |
1 LEVEL
|
15
OTHER CAREER HIGHLIGHTS
1
1 l
Yes ] Medium 1Polyworker )2 years or |Arrylon]t rl If |ResJ n Plant, |Also prior to |]950. 4 years| | RAF |ma1n tenance. ] 3 years motor |cac palnc&hop 12 years In I Graving Dock.
E6
OTHER COMMENTS
-^Ses
J High - 1 1 J Polycleaner |Heavy goods
j Inform at lor.
Imontbs ( 500| J966-67.
IvehicJe drlverlgiven In
1 ppm) Low- |Spray-d rler | un 11L final
H et ter
f 1 8 months Ibagger J967- | 1 ilnes.
[ I8.06.8i. ( c
1 ( 50 ppmj. 168. |Medium - j B1ow-down
J Dr D H J 1 Wi 1 llama
12] months (at ripper
| ( 200 ppm) |operator
11968-70.
Yes ittlgh
\. (Polycleaner
J 1965 -69 11965-68.
|Med 69-79 S Service
(Low 79-82 [operator
f68-69.
[Poly
J Operator
[69-79.
1 Leading Hand!
J 7 9-82,
Yea |Lnu 1957-59 I Spare man, I Hi kIf 59-74 IhaaRlnK 1 Low 7 4-85 |floor I J9 57-59. | Aist-nc ave | Opera tor 1 1959-85
1 Let ter of 104.06.85 1 Dr Paul SmIt 1 a nd letter > 104.06.85 |Dt D K D Eva 1OesophageaI 1 haemorrhage Idue to [oesophagea1 Jvarites due IAng1 os a rooms lof liver
S Let ter 526.06.85 ! Dr FI Lee
1
GEHC 006217
I'.ip
ck Sheet U
COUNTRY ANU NAME OK DATE tJF
REr ERE.NCK
INITIALS BIRTH
iK ]I
] i`E CJEEM1 CALS t> FJi it YMJ KS LIVEK Angiosarcoma Cases - (Review Date : 1 January 3 980)
wkx/amj i.anuocam
Ha r ry Barry
I2
FIRST VC EXPOSURE
DATE OE IHAG NOS IS
ACE A r I] [ AO NOS I s
YEARS OK
EXPOSURE \O IJ I AOSUS I
YEARS OE KX KOSURf,
DATE OF DEATH
H I s roLQGICAL Ci'S'h l KHA I [(IN
ESTIMATED h Xi'USIJ RK [ I VU
OCCIJJ'A [ JON
OThrR CAREER 31] OHJJ (pH r S
drill-K COMMENTS
1 Hlsn I E'o] yc leaner
1 |Moved cn
f | Remained we l l , working
1J968-69 Low 1 Ce n L ra t
f Ai ryl on 11 ri J e | actively, nut 1f Jan 3 906
|Plant until
|
f Depot
lleft BP 1903. 1
1 3 969-7 [J
]Manage r of
|
Hi a 1 Pnly floo r
j1C & SS Ltd at |
1 1970-197)
[Cardiff Alrportl
1
[1983-86
|
1 11
Ft 110 moriLlihl Kotyr lender
1 |
1 HIkIi
1 ] 966-6/
| 1 ll yea rs 1 Poly floor
1 |
| c onH tant |worker at times t
j He d 1 urn 1 between
|
|bu L on 11968-1982
|
1 j Let ten, t r r >i Or U.MU h-Vdiirt , | 3Ja t lio E s , Pen a r L li , W a 3 e h land Ur DMJ Ui1llama, HP, Ha
i J
1
[inter
1
1
l
im 1 t tent t 1 1
1 ) obh
1
!
1
1l
l
GEHC 003218
lI'IA Slu-Vt i
94
] i J Mil M M AI S A iJ(Jl YMI !<', I.IVI'H Arig I tin.il unci rune h - t Review Late: J Jau 19HH)
UK -H yC tnii. ut dales DAY - MONTH - YEAR
UPX/AHI, - I.AHiatiCASKS.J'l
MBJWJKY AND
Km HENCE NO
NAME OR INIflALS
DA'Jli OF BIRTH
E.irl Parks
1 02 1
f |19,08.33
BFG
1i
1f
1l
1\
1l
03
|Edward
125,05,15 BKC
|Dinwldd le 1
11
J1
1 04 l
1 |15.01,24
BFC
i1
11
f 05 1
( 325,01,12
BFG
1t
1 rl
1 06 1 Ray
1 123.11,28
BFC
| Aust in 1 Jones'
1 1
il
11
11
11
1i f:7 |Char 1es 103.05.22 UCC
\ T Sma rt
1
f1
1l 10 6.0 5.20 Goodyear
FIRST VC EXPOSURE
DATE OK E) 3 AC NOS IS
AGE At DIAGNOSIS
YEARS OF EXPOSURE TO
i>t m: nos e s
YEARS Oh EXPOSURE
OAEE Of UF.ATU
l.out h vt 1 le
1 | Lou 1s| vllle
1 1 1 J lLou Is| vi1le
1 1 1 ]Louis3 vi I Le ! 1 |Lou is| vllle
1 1 | Louis| vllle
t
\ 1 1 l 1 IS Cnarle| sc nr
1 t |Niuga ra
15,11,55 00.05.70
28.11.46 19.12.73 06.07,52 19.08,67 19.Q6.44 U9.04.64 17.01.62 00.02.74
27.0E.44 GO.OH,4E 1
i7 . LI. 4<i 1 0U.uH.fe:
1 1 1 1 r i i i i i j i i i i I i i I i i i i i i r 1 1
1 1 F 1
37
58 43 52 45
45 Hi
1
1 f 1
i l
J4
28 t5 20 12
) l
l1 1 t 5 127.09.71 1 j { N Ensil J |ays E i 28.09.7!) I1 1F 1 28 119.12.73 11
11 11 l1 1 J 5 107.0J.68 11 1l 1F 1 2D 109.04.64
1i 1F 61 1 12 (24,07.75 11 Fl 1t 11 1 11
1 1 l i I 2 i.u i, bn 11 rJ i1 t 1 5 3 29 .DH.ni
j
H t s rcu.oc t CAL CONFIRMATION
^fes
Yea Yea Yea Yes
Yes Yes
1 |
1
1 1 1 t |
1 F 1 1 f
1 i 1 |
1 1 3 f
1 1 1 1 i 1 1 |
1 1 1 r
ESTEMA TKI1 EXPOSURE
E EVER
orn'r'AT roN
OTHER CAREER JtlCHl IC1ITS
j | |
OTHER COMMENT.1
f
J History given (RolLlng Set.
Pol Cleaner (R1ork Jama
1974) p 53
in Annals NY |Art ACAD SCIENCES fKef 1 Vo 1 329 ( 1979) fof Sc page 190 In 11974
NY Ac Symp
Papci liy
IAIkii lUniV
IE IE Cm l t l ru ii t | J aiaa \ . / . ! u
OSHA
|p 53
j t Pot C.l eane r KU Film-k)
I
FRef | AJ ko Blink
1 iJAMA 1,7.74
1 Ip 53
1 1 | Pot E (Of
C! eaner Block)
j Lout avi 1 ]e | E'mir ler
1 1 l Re f 1 A1 so
Block
( 1 1 ( Pot F (Cf
Cleaner B!oek)
|Jou rnal j02-Q9-S0
1 f 1 |Ref (Also Block
11
E | Pot Cl eaner UCf Block)
1 1 Ref 1 |A1bo Block
1 1i 1 us Al r force |
{ f 1 Re f 1 +
1 | Pot F(Cf
1 i
CJ eaner Block)
1 Lou lav i 1 1 e ITJmee 23.7.7 [Re 11 red Apr t \ 1974 |A3so Block
r1 iJ j 1 Ret 1
i1 iF ii
i 1 Re f 1
SENC 008219
11 'iA
U I r Uf Ml',ACS h FUl.YMLK'i I, lVI R AngSnh.........Him ilmhOH - (Review |lriti`r l Ian MJKH)
UK system of Hares i>AY - MDN I ][ - YhAlt
WPX/ASL_2 - LANCIOCASES,1
('JlJ^TKY AND E h h I RE NO Nt)
NAME OR INITIALS
DATE OF US RTH
FIRST VC EXPOSURE
DATE OF IHACNOSJS
AGE AT J) I ACNOM li
YEARS OF EXPOSURE ]f)
UlAONWilS
YEARS Oh EXPOSURE
DATE Oh UFA I'M
IJI S [01,00 [CAE CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HICHLTCJITS
OTHER COMMENTS
Ra yraund Cel t3 eFj nger1
l,ou I svl J le
2fl.OS.45 01.03.74
16.06,1 3 Goodyear Niagara
12.06.51 00.05.68
27.05.09 Goodyear Niagara
14.10.46 00,03.70
Franc is A Bachrna n
Poc tatown Pa
Richa rd Edward Clendenin
03.12.21
S Charle ston
00.05.74
IJ.03.1 5
2000 pikti
Re I" I hart wrirn^; f [rui i r e first expos li re. I .mi i av i 1 ] e T t mea 29.10.74, 12,3.75, tO.3.76
07.04,74
High Ul yrs 10 yrs> as
Utility 6
reactor op. Seivice op.
(n ot t 3 e atie r lia^gtr
- separate Dryer op.
crew cleaned Stripping op.
a ut oc 3 av e b ) 3 yes prior
service In
tyre plant
Ref 1 + leti of 26 April S97H tn>r* Ru sse 1 i- A 101 to J T Seawe of MCA
2000 ppa
Charleston Dally Ha 11 21.7.75
Never diag nosed as ang iosarcoma of liver, I nfon at Ion given i i et te r 2 2 Ma 198- from J A Sa Ig .
Ac connt a nt, ASL - No evi dence of Vi'M e xpi>h li : e. f
GENC 008220
Mm l | !
Ml ( hi M I' AI S 's y\>[ r L11 Hi
I I VI' it An* ........ ........... ..........* I Itry f W I)...... I I 111 11.1M. I
IJh Syr. I r:n if . I j I I <>h DAY - MUNJM - YLAK
U'?J x / AM J - I AND I iH AM'H , 7
i (MINI H V AND VI KKHrNCK NO
NAME OK INITIALS
DATE OF BIRTH
FIRST Vt EXPOSURE
l>ATK WY DIAGNOSIS
Ai,l A'l IJ LAG NOS IS
YhAKS <JlEXPOSURE TO
DIAGNOSIS
YEARS Oh EXPOSURE
DA IF OK DEATH
H IS IOL0G I CAL CONFIRMATION
ESI IMA! KJJ EXPOSURE
LEVEL
OCLU FA rION
OlllbK CAREER J31CHLIGHTS ____
I f I I
OTHER COMMENTS
J 6 j James 104.11.27 BFG |Howard
1 1 1 1 1 1 1 1 7 | Peerenboou 106.05.31 BFG 1 1
1 1 1 1 18 f Chari 1 e 1 22.04,28 BFC lArthur
f 1
l LouisJ vi lie
l 06,05.50 1
11
1J
1t 11 11
1 1 Louis-
| vl i le
1
\ \ 23.06.55
11
11
ll
1! 11
1 _1 JAvon Lake| 15.09.54
11
l1
11
00.00,69 El. 10.74 00.00.75
E 1 1 1 1 1 1 1 1 1 1 i i i l 1 l
\ l l
4l 43 46
VIrul] Chris t ian
S Charle 00.00.43 ston
19.06.75
31.06.17 Coodyear Niagara
00.00.55 30,01,76
Chest e r HInklr
I' a r l y 7 i
19 1 04 | 2 7.03.69
Yes 1
| 1951-4 VCM j From 1954
ITaole 4 In
11
J
| polymer-
lonwards In
1 Wagoner
1i
1
(laatlon
{Army and other) Testimony t(
11
ri
| s e rv 1 ce.
|US Senate
!1
ii
|46-50 Army
( Con f 1 raned 11
11
ii
1
1M N Johnson
1l
ii
1
jltr 07.08.76
l1
ii
1
1
11
ii
1
1
19 l 19 1 16. 10.80 on 11.10.74 3
1
I
!Or K N Johns
11
but no
1
1
f
Hotter of
11
pna t "inn rt em 1
1
1
1 24,2,6 E ccm-
11
16.30.80
1
1
1
1 f 1 rmed <le a t f
11
11
1
j 6 years a f te
1l
11
1
Idlagnoste
1J 21 1 n ! 0 2. 1 l . 7 5
11
Yes
|13 y r s
|Navy
! 1
1 lCon firmed In
1l
|auloLleanerj
1
fM N Johnson
11
|B yrs on j
1
11tr 07,08.78
11
jtetol
ITyre Store 1
lAlao Rolling
plasticiser
I Stone nag.
& Carboaet
I IS.01.76
operatIon
2000 ppm
r I IUl1iLams port I Sun Ga^ette 121 June 1975 IChacteston l Dally Hall 121.7.75
J INIOSH letter lot 25.10.79 1 I I 2K yrs ui l h
HJUt at SC J Retlred l News re leant* 17 1.2. 7 7 I
GENC 008221
I'00'
6Sa Sheet 4
/H
LIVE Ft Angiosarcoma Cisi's - (Review |),ue: I J <i n L 9H h}
l)K system of dates DAY - HONI'M - YEAH
WRX/ASL l - 1,ANG 10CA6ES * j
J
i2
l1
4 15
COUNTRY AND r NAME OR 1 DATE OF REFERENCE | INITIALS 1 BIRTH NO
USA
22 102. JO.21
COMPANY 1 FACTORY
BFC J LoutsPV1 J U
FIRST VC EXPOSUKti
l J . 7,4 7
21
100,00.21 Great
|Ft tchburg 08.09.58
Ante rlcan frtess.
Ch etn 1 ca L
Company
24 1Charles 117.05.17 UCC
|S Charle-
1939
| Edward
1 ston
|Moore
( 7M
DATE OF D lAG N(JS [ S 00.01.70
06,04.73 27.05.77
1
81
9
1
AO r A'J
1 ( YEARS OF
DIAGNOSIS | EXPOSURE TO
1 DIAGNOSIS
1
1
5/ [ 1 1
79
1
1 1
i
1
1 1
1
1
1
1
1
1
1
t
1 50 |
15
1 3 1 60 | 18
1 1 1
1
l
1
t
1
1
1
J
(
1
1
1
[
1
1 JO | J 1
1
i
YEARS Oh | DATE IIP
EXPOSURE | JJEAJH
1
1 1
1
i Us2d |u\. 1 .
J
? 1
1 1
f
l 1
J 1
1 1
1
1
\
1
1
1
1 14 106.04.73
1 1
1 24? 127,05.77
C NIOSII
1
says 26) t
1
1
3
1
1
1
i
i \
1
1
1
f
1
1
12 HISTOLDGICAJ, CONE IRMAT10N
Yen
Yes Cholangtos arcoraa ( R Kaminski
26/ 2/79)
3 ] J4 1
1 35 J
\
16
ESTI MATED
I
EXPOSURE 1 OCCUPATION 1
LEVEL
1
OTHER CAREER HICHLICHTS
1 1 J. 1
OTHER COMMENTS
l
J
1 1 l.oui sv | i le
fTImea 26,3.
Isald he was
1 the I0t h AS
1 vlet 1m at
1 tic 11 6 Lane . Iwhom 8 had [died by
126.J.76 IIn his letti Jof 36.09.81
1 Or M N Johnh Iconftrnas thl
1 Is the
lease de&crll 1 by Dannahe r
| Tarabu r ro 6 Y 1 In Feb 1980
JAm J Medlcln
|Vo 1 70 p280 1 1
I
Medium to high for 24 yrs
|1941-65 non- 11937-39 was
1 solvent
[off and on
fvinyl resin llabourer
f unit and
t 1939-41 may
1 dispersion |have been
jvinyl resins Jexposed as
lunit first 1 reactor
(as fitter |c Leaner
1 hetper, then 11943 became
J shlf t
Ishift fitter
|u C11 1 ty man 11946 became
| shift utility
Inian
1 |N M Wheeler 11etter of |18.8.77 to IJ Stafford tgives detail|Ro6e Kaminski J1et ter of 126/2/79 fR Kaminski 1(5 Kou 1980) I suggests chat (NIOSH will Iretaln on
p 2 6.04.6 5
f register sir.i'
| emp1oyment uas|this neoplasm
| t e rm 1 ita t ed
Ima y be a e sol 1
| a t e<! with ASL
|R N Wheeler
fS I Re mu ,i f t row r l-^ [>(< r c ,hiJ rsilt'd in k Kaminski letter .it 5 IV-.jvein! er !9H'i
1 1
1
1 1 1 1
J20/2/M and | Roa e Xajn 1 ns k 5 1 1etCers nf J26/2/79 and 15/l 1/80
GENC 008222
USA. Sheet 5
I u * in .M i i AI 6 A I'lH.YMI lr. LIVER Angl osar coma Cases - (Review Date: l Ian ]9bB)
UK system of dates DAY - MONTH - YEAR
WFX/ASL__2 - LANGIOCASES ,4
l
12
13
COUNTRY AND | hi l>T Rh NO | NO
NAME OR 1 DATF. OF f N 1 1 EAI.S j BIRIN
11
LI 26 | John Be rry |07.07.23
27 |J L
1] 1.05.16
]Forrest
28 29 30 | WN
111.04.17 112,10.07 f 22.07.22
31 1
3
108.L J.23 1
11
1
4
1 3I6
I
7
COMPANY
11
t
1 t FIRST VC | DATE OF
| RAO TORY J EXPOSURE | IJ1 AC NOS J S
JL 11
1 1
11
1
AFC |Louis- | 03.10,47 | 00.00.77
| vli1e
|
I (up to 2
11
1 years
1f
1 after
11
1 death)
11 11 1f
1 1 I
11
1
11
1
\1 11
1 1
ucc
11
1
1t
1
11
1
1 S Charle-j 01.07.41 | 30.1 I.78
1 stun |
t
1l 11 11
l 1 1
11
1
11
1
ucc ucc
11 IS Charle- | 1 a too |
11 S Charle-I 1 ston |
1 00.06,44 I
1 1 00.05.42 1
1
03.11.76 00.03.80
f1
1
11
1
Tenneco I Flemi ngcon ]3.06.64 | 30.32.80
Chemicals 1
1
1
1r
1
J1
r
i1
i
91
I
i
UCC
11
i
| S Charle-I 12.05.46 | 01.06.81
1 ston |
j
11
3
11
E
11
1
11
1
1J
1
1f 11 91 13 11 11
f
1
1 1
J
1
i
11 11
\ 1 1
8
ACF A IJ 1 A<,NOS t1
11
f H 1 10 1 H
1 f YKARS OF
1 | YEARS OF j OAE'K OK
FXJ'UMIIO' HI | J'XFOSIJRI. | 1)1.A Ml
1 Ij 1 AGNUS 1 8
1
l1
1\
52 1 28
1 18 |J1.02,75
(dent h) 1
(J e,it h)
1
\1
[1
11
11 i1
1 11 1J
1f
1 1 1 1 62 37
1 1 1 1 1 1 6 1 34
f
1
1
1 | 20 | 25. 3 t.78
| (NIOSN
!
|eaya 27
3
land C
3
|Dally Hal 11
125)
1
1
1 \ 33 I 03.11.76
1
1 72 38 1 16 101.03.80
1
1
1 58 17 1 15 |30.12.80
1
1 3
i r
i
i 57 35 t 1 3 102,04.82
1
1 1
1
1
1
1 11
t
1 31
1
t1 11 1
1f
1
12 \ 13 1 14 |
15 1
16
f1
1
lusnu.ncirAi. | ESTIMATED 1
|
CONFIRMATION I EXPOSURE | nCOU FA 1'ION
| LEVEL 1
OTHER CAREER IIICIIL [CUTS
1 I
OTHER COMMENTS
1S
1
1 Yes t Exposed In |Various fobs
faomc decree| 1n PVC
|
[ R Karo nsk 1 | 1 el t e r nt
1 to 22
|pi ant s from
l2(>/2/7`) and
| r hem 1 c-a 1 s 11>uL main
Icold room to| |paste
|Prof . Tanbui 3letter of
lexposure
| recovery to
|waa to VCM |PVC charging!
19/1/79
1 probably
loperator to
Iblgh
[paste
J | charging.
i | 11i August
! 11965, | | Termlnated
1 jemployment
1 |Jan 3966
Yes
1
High
lOperator to [Exposure In
|R N Wheeler
1
110.10,76
|bulk and
I t t r of 4 Jai.
11
[dispersion FVC|19?9 and
11 11
{manufacture
[Charleston 1 Dal 1y Hall
f1
l 30. 1 l .78 and
1J
|R Kaminski
1 Yes r
1 |
J |
126/2/79 |R Kaminski
i1
1
| letter of
i Yes
1 1
1 1
16/4/79 |R Kaminaki
i1
1
ILecters of
i1
1
|19th June 191
i3
I
Yea |6 - Unknown |Ma1n t enance |
J6 5th Nov l9F
19 - Minimal |Me chanic
|
1
[6 yea
|
1 |Elsewhere J
3
1 ti yrs
1
1 j Boiler house|
E
lOperator
l
f
|9 yra
|
Yes
IHIgti (But IChemical
|From 1959 to 1 Dr Dace y
| n ut as hIgh JOperatur in |3 9 7 6 Aliphatic 1 letter
|as reactor jebarge
[Chemicals
I 16. 1 0.8 l a ml
|cleaner
ireactor
loperator and |R N Wheeler
fwould
1
|from July 19 76 |let te r of
|e xpe r1 once) 1
{to date
[9.11,61.
I Worked .is I
| tabouret
1
| t i urn
I
| June 194 1 1
11o May 19 4 6 1
| a rid ina y | hawo
1 1
| e leaned
1
j react n r s In
f X toil ( t INI' 1
|F o roman |Aliphatic J Chew I < a L [Operation
1
1 1
1 1 i
|Also Dr Dacey |1et te r of 107.03.81 re Idate of death
GENC 008223
USA Slice t 0
I > I i III I'h AI
I'i'l I'M I h
LIVER Ang l ubcircnma Case s - i[ Kir v l e w Lite: L Ian 196b)
UK tyHLiiin ot dates DAY - MONTH - YEAR
Wl' X / AM _l - S.ANi, lUCASES ,, S
11
i
12
]
COUNTRY AND | REFERENCE | NO
NAME OR t INITIALS (
DATE OF BIRTH
US 32
|C W Cirouxl 22-02-08
US 33
|S Fergusonl 08-10-27
4 C0KPANY Honsanto
BFG
1 15| 6
1\
1i 1 1 FIRST VC | FACTORY | EXPOSURE
11
11 11 Sprlngfield 15-10-51
1 Hass
|
11
11
11 11 11 11 !1
l1
1E 1f
1l
11 11
11
11 11 11 11 |Louisvi1le
09-09-54
Hr Syrian
Louisville 1955
S Chat 1e^ ton
The GeneralfAsh tab
Tire and
i !'l a
Rubber Co
I 1-06-56
DATE OF E) I AC NOS IS 00-07-79
l 1-05-82
1 8 I 9 1 u>
1
AG E AT
| YEARS OF
1 | YEARS OF
DIAGNOSIS | EXPOSURE TO | EXPOSURE
DIAGNOSIS 1
1
1
71 1 28
1 14
|(in PVC
| a Lit 04 1 ave
Jarea}
f ! 1
1 1 1 1 1
1
1
1
1 1 1 1
11 DATE OF
DEATH
1 7-05-80
54 | 26
1 28
A1 lve
1\
2 1 U 1 14 f 15
\1
1
11
1
HISTOLOGICAL | ESTIMATED 1
1
CONFIRMATION 1 EXPOSURE l OCCUPATION [
OTHER CAREER
1 LEVEL 1
3 HIGHLIGHTS
i
An autopsy
i 1 Th e death | L 940-!9 51
|
was done and IcerLlflcatt |Varlhub j obs|
1 rained 1 ate
Igave
| i n po 1 ycne r |
c a use o f
{Mr Giroux' | nia nu t ac t si re |
death given |us ua1
|BUTVAR
t
as
|o ccupa 11 on iLUSTRKX
f
Angiosarcoma' | as '"ke 11 le| 3 951 -1 964 s
\o pe rat or" IVarloua 1ob&|
1 In
| X n a nd
|
f"chemical a {around PVC I
1E nduat ry". |auto c1avea |
E 11964-1973 |
l
[Various
|
1
| clerica1
|
1 {jobs in PVC |
1 Ipolymeri&atlon
1
| fac1 It t y/
|
1
| Ret 1 red
j
1 101-03-73. |
1 Yea 1
i {Multiple
Joba
1 |
t nc1ud i ng
Poly
Operator + I Po1ycleaner. ^
Poly
I 11965 left BFG
Operator + |t o become a
Au t oc t ave | Clergyman.
Cleaner
1955-65,
I
1
16
OTHER COMMENT l
Informat 1 oi g iveti 1 n letter of 7 Februarv 15 from Dr Walter C Barnes of Honaant o Sprlngf ield Dr A Mu nil n Hons an t o Eu rope.
Prof Tambur1 letter of 12 Aug 1982 Dr M N Johrs1 etter of 28 Feb 1983.
Dr M M John.! letter of 3 Nov l982 , 28 Fe& 1985 and 9 Aiig 198m .
IHlgh from
l I 9^ to
I 1 9 55.
| Me d 1 mi' f rom
13955-l958
1 \ Moderate
1956-56
1 a bou rer
1956-57
I
p rod helpe r |
1957-7(1
|
operator
j
1970-75
|
elect rlclan i
1975-prenent|
operator
t
_L ________ I
Dr Dacey teeter of 5 Sept 19ft 3.
R U I.au ndrie tetter of 1 2 Sept 198 3 spotted at medleal Hay 1983, Test lag c oracne need Kay 1983
GENC 008224
IMA
Mi. .
jJ
t,II. I "I M' < AI
!' J1 YHt- Kii
I m'I h An/ I........................ ( ..........
Mk v I , w ............ I ............ i y I MHIl)
UI'X/ AS I i I ANl11 lHlA.se!. ,
UK h y.H 1 cm u f i hi t i'm HAY MOMH 1 All
]
(OUNIKY AM) KhhERENCK NO
USA
37
38
39
1 12 1 1 ! MAKE OV 1 INI runs
1 1 1 | Mr J !Pay tun 1 1 1 1 1 l E E 1 l JWB
1 1 l 1 1 1 t t 1 1 1 1 1 1 1 |J Hemice 1 1 1 1 1 1 1 1 1 1 1 1 1 1
l 1 1 j
1 1 1
1 3|
4
1
1 UATh 01\
BIRTH | COMPANY
1 1
! 29.08.29| BFC
1
1
1
1
1
1
1
1
1
1 28.08.221 Ai r
|Products
1
l
1 1 1
1
1
1
1
1
1 t 1 1 27.06.18)Pantaaote
!
1
1
1
1 1 1 1 1
f
l E
1
1
1 l
1
1
i 1 1
1 1
15 | FACTORY |Louisj vi ] le
(Calvert iCity
iPassaic
-
1 16
1 1 |FIRST VC | EXPOSURE
1 1 1 1 1953 1 1 S 1 1 1 1 1 1 1 100.02.63
l E \ E 1 1 \ 1 1 1 1 J 1 1 1 1 1960 1 t r i i i i i i i i \ i i r l 1 1 1 j
i f i
J ! 1 8 19
1
EYEARS OK
|DATK OK l m;p at |EXPOSURE
|DIAGNOSIS| DIAGNOSIS!TO
|DIAGNOSIS
1
1 106.08.84 | 54 1 33
1
E
1
1
1
1
3 1
1
1 1 19.01.84 | 6 ] | 20
1
1 l
1
1
1
1
1
1
1
1
J i 1
| March 11984
| 65 |
i t 24 \
1
1
1
1
1 1 1
1
1 i
iI I1
1 1 l 1 1 j 3
1
in ] \ KHARS OK DATH UK EXPOSURE UEA TH
22 06.08.84
20 28.30.83
23 29.06.84
11
1
1
1 13
1
E4
1 J5 1
16
11
1
IHISl'D- |
1
lUM.W'Al, \ KS ! 1MA t ED J
|OTHER
1 CONFIRM-|EXPOSURE |OCCUPATION I CAREER
J
OTHER COMMENTS
iAT ION |LEVEL
1
I HIGHLIGHTS!
11
E
11
11
1
1 Yes 3 High | Worked
\[nformarE mi given Mi letter 09,08.
1J
|reguIar ly
| f ruin Dr .H N Johnson
1i
J1n PVC a rea
|In the
I1
iea r1y days
11
(was a
11
Ereactor
11
| c 1 easier
11
1 1953-7 5.
11
1
11
IThroraho cytopenla and leukopenia since
1 Yes l High |Normal
Istnce 1978. Cold treatment for arthrltt
| t 196 3-19821 progression
11976, Under Dr's care about 6 montlia
J1
| f rocn helper
Jbefore death, had passed standard physic
1I IE
| to senior 1 o pe ra to r ,
J exatni nat Ion 3 months earlier. J Barr (letters of 22,ED,84 and 23.01,85.
1E
jc Leaned
E1
j reactors,
lf
I stripping
11
land
f1
1 recovery
11
Eareas as
E1
Ewell as
11
[charging
11
loperator.
11
1
j1
1
1 Yea 1 Low | 29.09.60 - | Worked
{ Never In hospital for any chronic or (acute medical problems. Death certlfLcac
11
| May 6 6
| before
Jstates cause of death cardlo-pulmonary
!! 1E It
\Vinyl
11960
\ Fabrl cat ioi |wltb US
1 PI ant
E Ai r
(arrest secondary to angiosarcoma of (liver. (t.etter of 15.07.86 from. John - Ertel
t
1 High | Ha y 66 - [Force,
|of Pantasnte with letter of 24.02,66
S1
I Aug 70
lUntted
l t rom Or Auerbach, FJa t li o l ng t s t,
(1
ll'tll ity
| Wo o t
f1
S Rest n
|Dye rs
11
(Operator | d nil
11
| { 1 nr Ini bf- f Ok a ii l t e
11
|- Sep 6 7
1i
| Reactor
I Ope rator) S
| 1 [iiu J 6e j> 70--8 2 i
11
E Ho nome r
tl
EUperator
| | Low | 3 982-8 i
11
| Ml 1 L
11
| upe r.it nr ,
11 1i 1E
| (.a Umis1.it | Shop , u iii J 3 | ret E rerne n r
1r
1
GENC 003225
,,SA SUee t b
[U LH M [ CALS 6 HOi.'rMb'RS LIVER Anglobdrcocnri Cases - (Review Date: 1 January 1983)
WPX/ASL2 LANGIOCASE S,7
UK system of dates UAY - KONtH - YEAR
l
COUNTRY AND REFERENCE NO
USA
40
43
1 \2
3l
1 4I5
J 1 | NAME OR
1 INITIALS
DATE OF | BIRTH |
f 1 i COMPANY | FACTORY
11
1 1V P
26-10.141 BFG
1 I f Loule-
IClime r
|ville
11 11 i1
\t
1
ii IS Buckley *> 1915 | Coodyear
1 J 1Niagars
1 1J
1 1f
1 11
l 11
1 lj
1 16 1 1 |FIRST VC j EXPOSURE
1 1 1 122.05.42
1 S 1 1 1 1 1 l ? tale 1 ]9401s
1 1 1 l
7 i a 19
10 |
]t
1 J
J E 33
l | 14
i 1 15 1
16
DATE OF 1 ACE AT
1I
1 YEARS OF j
|HISTO- 1
f EXPOSURE | YEARS OF| DATE OF 1 LOGICAL | ESTIMATEDl
i I |OTHER
D LACh'OS IS IDT AO NOS IS I TO
| EXPOSUREj DEATH
1 DUG NOS IS |
lCONEIRM- [EXPOSURE |OCCUPATION [CAREER
|
f ATION j LEVEL
[HIGHLIGHTS
OTHER COMMENTS
13
J
1987 1 72 1 45
11
I
34 1 03.01.87 1 Yes | High |Chennl{al t
1
| 194 2-19?4| Wo'rt er
1
[Letter from Dr Dietz, BFC, 110.3.67
11
11942-45
1
1 1 Low
1
1
J1 97 5-19761 Foreman
l
1l
11945-76
E
11
1
3 987 1 72
1 ? 4 0+
1 If) f A S 1 v e approx |
l | *' Yes
1
1 1 1
1 1 | Letter 1 rom Prot Taraburro 1 [University of Louiavllle
1t 11
1 [
11
i
1
1J
J_____________
GENC 008226
HilgV Ut,uSLAV [ A
C11LrN l K AND HI FFHfcNLE NLJ
NAME OR INITIALS
DATE OF BIRTH
[Cl CJib-.MJ CALS f, POLYMERS LIVtS Angiosarcoma Cases - (Review Date: l Jan 1986)
12
FIRST VC EXPOSURE
DATE OF DIAGNOS[b
AGE AT DIAGNOSIS.
YEARS OF EXPOSURE TO DIAGNOSIS
YEARS Of EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRHAT I ON
ESTIMATED EXPOSURE OCCUPATION LEVEL
OTHER CAREER HIGHLIGHTS
WPX/ASL - LANGIOCASES,3J OTHER COMMENTS
Jugo Vlnli
Spilt
00.00.53
Jugo Vlnli
Split
11.06.30 Jugo Vlnli
Spilt
VCH Froduc tIon
SARIC et al paper Env Health Perspective Vo: pp 189-192 1976
Mn his letter of 3 Oct 1976, Dr Spirtas of NIOSH changed the statue of Case 02 to VCH production employee. Dr Spirtas also notified a new Case 03 also a VCH production worker.
Rose Kaminski letter of J9 June I ARC letter of 1 April 1982
6ENC 008227
(Review Date - 1 Jan 1988)
I nc i <1 ciicc ol ASI, Gases l'r r Annum
By date of death
198 8 ........................................................................................................................................ 1
60
7 .................................................................................................... I
8 .................................................................................................... 0
90
I960 .................................................................................................... 0
1 .................................................................................................... 1
2 .................................................................................................... [
3 .................................................................................................... 0
4 .................................................................................................... 2
5 .................................................................................................... 0
6 . ............................................................ 0
7 .................................................................................................... I
8 .................................................................................................... 5
9 .................................................................................................... 3
1970 .................................................................................................... 2
1 .................................................................................................... 3 2 .................................................................................................... 5
3 .................................................................................................... 8
4 .............................................................
5
5 ..................................................
11
6 ........................................................................................ 11
7 .................................................................................................... 9
8 ........................................................................................ 10
95
1980 ..................................................................................................... 10
1 .................................................................................................... 5
2 .................................................................................................... 3
3 ..................................................................................................... 10
4 .................................................................................................... 7
5 .................................................................................................... 6
6 .................................................................................................... 3
7 .................................................................................................
Total
129
N.B 1 Does not include Italian 01 but does include German 03.
2 The 1977 total includes US case 24 which is a Cholangiosarcoma.
3 Does not include the following who are still alive, so far as known: Canll, Frl5 & 22, G31 & 32, 1JK14, US33, 3-'
GENC 00822S
p1.aie
35
T) i s L r i bn I: i mi of AS1, (Rises; h v Gnu n l ry
(Review Date - I Jan 1988)
i
USA W Germany France UK Canada Sweden Italy Yugoslavia Japan Czechoslovakia Belgium Norway
38 * * * 31 A A 22 *** 13 * ** 12 ** *
5 * ** * 5* 4 ***** 3 2 2 1
Total
138
* Omit ItOl - atypical case of PVC bag extrader. ** Includes G03 aerosol can filler. *** Includes case US 24 which was diagnosed as Cholangiosarcoma; & Can 1t , Frl5 & 22, G31 & 32, UK14, US33 , 36 & 41,
who are still alive, so far as known. **** Includes one monomer worker. ***** Tncludes two monomer workers.
i * e Western Europe North America Rest of World
Tota 1
79 50
9
138
WRX/ASU2 - LANGIOCASES, 10
GENC 00822?
)6
^^^ttern of ASL Cases by Factory
fc\BLE 3
( Rev i CM I)rh [ (' - I da I) I 9B8)
(;i) W liurope
Of the 79 cases in W Hu rope, 68 have nr cur rod in clusters at 12 factories. Of the 11 flernian cases , 28 ha ve occurred in clusters at h I .i r to r re s .
ASL Cases
Dynamit, Troisdorf, Germany
12
BP, Barry, UK
10
Wacker, Burghausen, Germany
9
Atochem (formerly Chloe Chimie, formerly RP), St Fons, France 8
PCUK, Brignoud, France
7
Kemanord, Sundsvall, Sweden
5
CWH, Marl, Germany
4
ICI, Hillhouse, UK
3
Solvay, Tavaux, France
3
Lonza, Waldshut, Germany
3
Solvay, Jemeppe, Belgium
__ 2
Atochem, St Auban, France
_2
68
MB: There are 32 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref Table 8)
(b) N America
Of the 50 cases in N America, 42 have occurred at four factories out of a total of 55 factories. In N America 43 plants have not had ASL cases.
ASL Cases
BFG, Louisville, US BFG, Shawinlgan, Canada UCC, S Charleston, US Goodyear, Niagara Falls,
US
15 12 10 _5 42
MB: There are 29 pre 1962 PVC plants in N America; 12 of these have had ASL cases (Ref Tables 9 & 10)
(c) Rest of World The 9 ASL cases are helieved to be in one cluster of 4 and two clusters of 2 cases.
WPX/ASL2 - LANGIOCASES,11
GEMC 008230
Page 37
^^LE 4 A
(Review Date - 1 Jan 1988)
Y1],.1 rii[ y I'cr I ikIs ( imi
1 t i mi 1 i i [ Ex pn< mil1 i i j 1 > i. 111 n r j , > ')
Country
No of Cases
Total Years
Average
W Europe
Be 1gium France Ge rmany Italy
2 35 17.5 22 574 26.09 * 31 632 20.38 *
5 99 19.8
N America
Norway Sweden UK
i 22 22
5 122 24.5
13 293 22.53 * 79 177 7 22.49 W Europe Average
Rest of World
US Canada
37
955
25.81 *
10 205 20.5 *
47
1160
24.68 N America Average
Czechoslovakia
2
30 15.0
Summary
Japan Yugoslavia
3
4 2
59 19.66
85 21.2 174 19.33 Rest of World Average
W Europe
79 1777 22.49
N America
47
1160
24.68
Rest of World
9 1 35
1 74 3111
19.33 23.04 * World Average
* Of the countries with > iq cases, France, and USA have an average latency period above world average; Germany, UK and Canad below world average.
NB: Does not include Canll or 12, or US41: details not known.
GENC 008231
Page 3 8 ^^TKriiiiTroN or
latkncy
pkridds
taijlk
a is
(Review Date - 1 Jan I y88)
11
1t
j ( -9 yrs 1
11
11
I Belgium
1 t
1 I
I Canada **
1 1
f 1
1 I Czechoslovakia 1
1 !
1I
1 France
1
i
1 Germany
f i
I i
1 Italy
I 1t
1 Japan
i i
I Norway
1 1
i
I Sweden
1 I
i
I UK
1 ! 1i
1 1 USA ** 1 i
1 Yugoslavia
1 !
i i
1i
I TOTAL **
1i i 1i
ii
i i 10-14 yrs |
1 1 1 1 1 31 1 11 1 11 J 5! l i l 1 l i l i ) i l 2i i i i i 12 i i
1 5-19 yrs |
21
11 41 91 21 1|
21 5| 71
33 |
1 f 20-24 yrs j 29-29 yrs 1 ! 1 1 i
5
3 10*
2 f
2 1
1 9 4
37
2i i 1 1
81 i
5I i
11 1 ! I 1 i
2! 1
41 1
8I 1 1
f 1 30 1
1
1 1 10-14 yrs I
1 1 1 1 1 1 1 1 1 31 i 0i 1 ! 1 ! 1 1 ! I1 j 21 I 5i i i
i i 13 i
i
3')+ yr. 3
6 9
1 1 f
i i i i i ! 1 1 1 1 1 J 1 1 1 1 1 1 1 1 f 1 f i i i i i t i
11 1 Ave rage |
Tot a 1 1 Latency |
1 Period
1
I (Table 4A)!
11 2 1 17.5 I
1i
10 1 20.5
|
11 2 1 15.0 |
11 22 1 26.09 |
1| 31 ] 20.38 1
1 5 1 19.8
1 |
jJ 3 ! 19.66 f
1 1 1 22
1 [
1E 5 1 24.5 1
!1 13 1 22.53 |
Jf 37 ( 25,81 |
! 4 i 21.2
1 |
I1
1 135 i 1
t 23.04 1
11 1
* Includes G 03 aerosol can filler
** Does not inc 1 ude Can 1 ! or 12, or l'S4 1 : details not known
WPX/ASL2 - LANGIOCASES,13
% GEMC 009232
is
1 Review ante 1 January i98Sj
TABLE 4C
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE
t MAX " SSIBLE 1
YEAR OF
1
! late:
PERIOD 1 FIRST EXPOSURE |
LATENCY PERIOD (NO OF YEARS)
| ARITHMETIC MEAN
1
| OF LATENCY PERIODS 1
11
_A
1 1939
1 38*
1 1940
1
11
|1
1
289 = 36.12
I
- f 1 1 1 37,21,37,41 -' 1 2 1 32,38,45
|8 |
1 1
-- 1 3 ! 38,14,32
|
1
1
4
1 28,11,24,20,24,34,39 |
718 = 26.59 1
1 5 I 27,22,28,29
| 'll
1 6 1 21,29,31,26,28,15,23,1
1 1
1 1 30,35 I 7 I 29,24,29,28 * 7* 1 8 1 28,24,34
| 1 |
1 1 1
1 9 I 30,26,20
| 521 = 24.80 1
1 1950
1 26,22,31,19,23,14,33 |
21
1
1
l
1 19,28,17,28,34,29
I
2 5 1 2 I 21**,15
|
3 - 1 3 I 25,22,23,22,20,31,22,1
1 1 1
1
| 32***
|
1
1 4 1 21,21,25,25,21,28***,!
1
1 1 22
| 787
22.48
1
I
5
( 22,23,24,14,19,21,27 t
"35
1
1
| 27*** 24,28,30***
I
1
I 6 I 21,12,27***
|
1
3'
I
7
1 19,17,15,13,16,28
1
I 0 I 8 1 18,18,15,17,20,29*** |
1
1 9 I 16,21,25,27
1 544 = 18.75 1
1 1960
1 13,18,21,25,24,25
I
29
1
1 1 1 15,16,16,16,19,19,12 |
1
_-
1
2
I 13,18,17,12,18,21
1
1
3 - 1 3 1 16,17,20,21
|
1
1 4 1 16,17
l 221 = 17.0 1
! 5 I 11,19,20
| 13
1
1 6 I 9,18,21***
|
1
I . 1 7 116
1
1
; - 1 8 | 18
|
1
1 9 113
I
31 = 15.5
1
1 1970
I
I2
1 VIOLA
11
1
I" 2 1
!
1 _ 1 3 1 v 1 1 M ALTON I
1 4i
i 1 GOODRICH
1 TOTAL
| 135 CASES
| 3111 = 23.04 . 1
1I
1 135
I
* Choi angiosarcoma ** Aerosol can filler *** The following are scill alive, so far as known Frl5 and 22, G31 and 32,
UK14, I' S3 3 and 36
N3: Does not include Canl1 or 12, US4 1 : details not known
WPX/ASL2 - LANGIOCASES,14
GENC 008233
TABLE 4D
LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL
LOCATION
"'
MAX POSSIBLE 1
YEAR OF
1
LATENCY PERIODS IN
LATENCY PERIOD 1 FIRST EXPOSURE I
WESTERN EUROPE
I
NORTH AMERICA
1 48 1 47 1 46 ! 45 1 44 1
1939 1940
1 2 3
I 1 1 1 37,41
1 1 38
1 1 38* 1 1 21,37 1 32,38,45 1 14,32
1 4 1 28
1 11,24,20,24,34,39
I 5 I 27
i 22,28,29
1 40 1 39 1
6 I 21,29,31,33
7 1 29 8 i 28,34
1 26,28,15,23,30,35 1 24,29,28 1 24
1 9 1 30,26
1 20
1
1950
1 26,22,31
1 19
1 35 1 34 1
1 1 19,28,34,29, 2 1 21**
3 1 25,22,22,32***
I 17,28 1 15 1 23,31
1
4 1 21,21,25,25
1 21,28***
1 5 1 22,23,24,27***24, 28| 14,19,21,27
1 | 30*** 1 6 1 21,12
i 1 27***
30 1
7 1 19,17,15,13,28
1
29 1
8 I 18,18,29***
1 15
1
9 1 16,21,25,27,
1
1
1960
1 13,18,21,25,25
1 24
I 1 1 15,16,16,16,19,19 1 12
25 1
2 1 13,18,17,18,21
1 12
24 1
3 1 16,17,21
1 20
1 4 1 16
1 17
1 5 1 11,19
1
1
6 1 9,18,21***
1
20 1 19 1
7 1 16 8 1 18
1 1
1 9 1 13
1
1 VIOLA 1970
1
1
1I
1
1 21
1
1 MALT0NI 3
1
I
1 TOTAL CASES
1 79
1 47
* Cholangiosarcoma ** Aerosol can filler
*** The following are still alive, so far as known Frl5 and 22, G31 and 32, UK14, US33 and 36
1 ROW 1 1 |
1 1 1 1 1 1 ! 1 1 1 23,14 1
1 22,20
1 22
1
1
1
1 16
1 17,20
1 11
1
!
1
1 1 20
1
1
1
1
I
1
1
1
1
19
NB: Does not include Canll or 12, or US41: details not known
WPX/ASL2 - LANGIOCASES,13
GENC 008234
TABLE 4F.
Utluf
s i fi 11U ci t v
PLANT
LOUISVILLE USA
TROISDORF W GERMANY
SHAWINLGAN CANADA S CHARLESTON USA BARRY UK
11 1 START |
1 UP
|
I DATE |
11
i1 1 1940? |
I1
11 1 1954 |
11 11 1 1943 | I(1941?) |
11 1 1939? |
1 1 1 1948
1 1 |
11 11
LATENCY PERIODS OF ASL CASES IN SPECIFIC PLANTS (10 OR MORE CASES)
i 1
| |
12,14,15,19,19,20,24,27,28,28,28,29,29 31,45
1
1 | |
12,13,16,16,18,19,19,21,23,25,28,29 11,12,14,21,22,23,24,24,26,28
1 |
1 1 |
24,30,32,32,34,35,37,38,38,39, 9,17 , 18,28,31,33,18,19518,21
1 1 |
1 1 )
1 1
1 NO OF | CASES |
1 1 1 15 |
1 12 |
1 1 10 |
1 1 10 | ! 1 10 1
1 1
AVERAGE LATENCY PERIOD
24.53 years 19.9 1 20.5 33.99 21.20
: Does not: include cases Canl 1 and 12 at Shawinigan: details not known
vPX/ASL2 - LANGIOCASES,16
GENQ 008235
TABLE 4F
.JfU
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT (10 OR MORE CASES)
Yr_AR OF FIRST | LOUISVILLE!
EXPOSURE
| USA
I
1939 1940
1 ]
1 1
TROISDORF W GERMANY
| SHAWINIGAN 1 S CHARLESTON 1
| CANADA
1 USA
1
1
1 38
!
11
1
BAK3Y CK
11
1
21
1
31
1
4 1 20
1
5 1 28,29,27 1
1 21 1 1 14 1 11,24 1 22
1 37 1 32,38 1 32 1 24,34,39 1
1 1 1 1 1
6I
1
7
1 29,28
1
1 26,28 1 24
! 30,35 1
1 1
8 I 24 91
1 1
11 11
! Ip
1950 1 2
1 19 1 1 13
1 1 29 1
I 1 1
1 1 1
1 31 , Vi 1 28 1
3 1 31 4 I 28
1 I 21,25
1 23 1
1 1
1 i
5
1 14,19
1 23,28
1
!
1
61
1 12
1
1
I
71
1 13
1
1
1
81
I
11
1
91
1
11
1
1960
1
1
I1
1
11
1 16,16,19,19, 1 12
1
i
2 1 12
1 18
1
1
I 18
31 41
1 1
11 11
1 17 I
51
1
11
1 19
6!
1
11
1 9,18,21
71
1
11
1
8I
1
I1
1 18
9 I 11 1
1970
1
1
11
1
1I
1
11
!
21
1
11
1
NB: Does not Include cases Canll and 12 at Shawinigan
V
details not known
X/ASL2 - LANGIOCASES, 17
6ENC 003236
v iae v i. cw a a re I Janu a r a i S 8 8 )
TABLE 4G
PLANT
| START-UP DATE 1 LATENCY PERIOD OF ASL CASES | NO OF | AVERAGE PERIOD
1 | IN SPECIFIC PIANTS(4-9 CASES)| CASES 1
1 BURGHAL SEN |
1933
11 1 17,21,22,25,24,13,21, 32,30 | 9 | 22.77 years
W GERMANY |
1
1
ST SON'S
1 |
1939
1 1 21,28,29,37,38,27,41, 34
1 | 8 | 31.88
FRANCE
|
1
1
BRIGNOUD
1 |
1950
! I 11,16,18,26,30,25,34
1 7 I 22.85
FRANCE
|
t
1
1 SUNDSVALL |
1945
1 1 16,19,27,29,31
I 5 I 24.4
SWEDEN
I
i
1
NIAGARA USA
1 | 1
1947
1 1 15,17,21,23 1
.
1 4 1 19
1
SPLIT
I | 1950
1 I 20,20,22,23
1 4 | 21.25
YUGOSLAVIA!
i
1
11
1
MARL
j 1948
| 15,16,22,21
4 1 18.5
W GERMANY |
!
i
11
i
NR: Does not include US41 (Niagara): details not known
WPX/ASL2 - LANGIOCARKS,18
GENC 008237
TABLE 4H
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT (4-9 CASES)
YEAR OF
1BURGHAUSENl
FIRST EXPOSURE 1 W GERMANY 1
11
1939 1940
1 2
1 1 1 1 1
1 1 1 1 1
3 4 5 6 7 8 9 1.9 50 1 2 3
1 ! 1 1 1 1 1 1 1 1 125,32
1 1 1 1 1 1 1 1 1 1 |
4 1 21
|
5 122,24,30 |
61 7 1 17
1 |
8 9 1960
I
1 121
1
1 1
11
1
21 31 41 5I
1 1 1 1
61 71
1 1
81 9 113
I |
1970
1
1
1t 21
1 1
11
ST FONS 1 FRANCE 1
1 1 1 1 37 41 1 I 38 1 1 1 29 I 1 28 ,34 |
1 1 1 1 I 1 27 1 21 1 1 1 I 1 1 1 1 1 1 1 1 1 1 1 1 1 I
BRIGNOUD FRANCE
26,30 34
18 16,25
11 1
SUNUSVALL SWEDEN 1 1 1 1 1 1 1
1 1 27* 1 31 1 29 1 1
1 1 19 1 1 1 I 1
1 1 1 1 1 1 1 1 16 1 1 1 1 1 1 1 1 1 1
NIAGARA USA
15,23 17 21
SPLIT | MARL
YUGO-|w GERMANY SLAV 1A1
1 1 1 1 1 1 1 1 I 1 1 1 23* |
1 1 20 | 22 22* |
1 1 1 20 |
1 1 115,16 I 21 I 1 I 1 1 1 1 I 1 1 1
*Monomer worker
NB: Does not include US41 (Niagara): details not known
WPX/ASL2 - LANGIOCASKS,19
GENC 00873G
TA!([,!-, ')
( I'Vu i
l>ul >'
I nil
Annual 1 nr i iln urn ol AS], 6.
fltulo r > I ili'ulh) by Grog rn pb i a 1 Area
1955
7
1961
2
4
t7
8
9
1970
1 2
3 4
5
6
7
8
9 1980
1 2
1983 1984
1985 1986 1987
TOTAL
1 111 | Western Europe | North Ame rica [ Rest of: World [ Annual Total
1 11
1
ii
1
1
fj
1
I
ii
1
1
ii
1
1 11
ii i
!
1
1 I1 !1 11
14
i1
13
I5
12 t1
12 I1 14 12
1 1 1 1 1 1
I
16
14
1
t6 16
13 13
t i
|7
12
!
15
1
1
t6
I4
1
15
11
1o 12
i
1
17 15
!3
12
1 1
15
1
I
!3
1
1
1
I1
1
j
7 -k k
|
46**'
1
1
11 1I 11 I1 l12 11
15
f3
12
13
15
3I8
-1 5
1 1 11 2 1 11
I9
1 1 10 -15 - 1 10
-1 5
13
1 10
I7
116
f3
11
9 I 129
I Cumu1 a t i ve 1
1 Total
1 Key Events
1
11
12
1 t
1
13
14 16
|7
1 12
1
f
1 1
!
1 15
I
1 17
| 20
1 25
I Viola
I
1
I 33
I Maltoni
| 38
t Goodrich
| 49 | 60
1 1
( 69
1 79
1 84
| 94
f
1 1 1
| 99
I 102 | 112
1 1 1
I 119 [ 125 | 128 | 129
I
1 1 1
1
* Includes G03 aerosol can filler but omits It 0 1 bag ext ruder
** Does not include the following who are still alive, so far as known: Canll , Fr15 and 22, G31 & 32, UK 14, US33 , 36 & 41
W!J X/ AS 1,2 - LANGIQCASES , 20
6ENC 008239
TABLE 6
ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING It.01)
1 KEY I
i 11
1 EVENTS 1
| WESTERN EUROPE
| NORTH AMERICA
| REST OF WORLD|
i1
I 11
1 1 1955
c
1 17 18
1 1 Cl 1
I C2
i
11 11 1|
1I 1I
19
! 1 1960 11 12
i
t
I US8
1 C3
1I 1I 1I 11
13 14
1
I US5
1
1 Cz2
1
|
15 !6
1 11 1 11
1 7 1 FI 18
1 9 1 G1
| C4,C5,US4,US7,US10 | US12,US16
1 1 1
1 1 1
I Viola
| Mi 1toni
I 1970
11 12
3
I Swl I G2 I N1 , Sw2 ,1JK 1 ,112 | G3**
I US1 1 | C6,US2 I C7 | C8,US1,US3,US23
1 1 1
1 Yl,Y2,Czl
1 1 1
]
|Goodrich 1
4 I G4,G5,UK3
I C9.US13
1
1
1 5 I F2,F3,G6,G7,G8,It3
| US6,US9,US18,US26
1 Japl
|
1 6 I B1,F4,F5,F6,F7,Sw3
| US19 ,US20,US2 2,
1 Jap2 ,Y3
|
1 7 I F8,F9,G10,G11,G12,Sw4
| Cl 0,US21,US24*
1
1
1 8 1 F10,F11,G9, G 1 3 , G1 5
| US27.US28
1 Y4
|
I G16 ,G 1 7
1
1I
1 9 I FI 2,FI 3,UK4,UK5,G18
1
11
1 1980 1 UK6, UK7,G19,Sw5,G20,G21US | US17, US29, US30,US32|
|
1 1 I It4,Fl4,UK8,G22,G23
1
11
1 ?. 1 G26
I US31.C12
1
1
1 3 I UK09,It5,F17,B2,G24,G25,G30| US35, US34, US38
I
1
1 4 I UK10, F16, FI 8, G27.G29 | US37,US39
1
1
1 5 1 UK11, UK12,FI9,F20,G28
I
1 Jap3
1
1 6 1 F21,UKl3,lt6
1
11
17 1 Total 1 74***
| US40 | 46***
11
19 I
1 I 11
* Cholangiosarc.oma
v
Aerosol can filler
*** Does not include the following who are still alive, so far as known:
Frl5 & 22, G31 & 32, UK14, US33, 36 & 41
Canll,
WPv ASL2 - LANGIOCASES,21
6ENC 008240
vw vit dJie i January
TABLE 7
ASL CASE NUMBERS BY YEAR OK FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING It.01)
KEY EVENTS
Viola Maltoni
|1
1
|
I WESTERN EUROPE
1
11 11 1 1939 1
1 1 1
1 40 1 1 1 1Frl1,Frl6 1 ?1
1 I |
1 3 I Frl4
1
1 4 I UK1 i 5 I Sw2
I I
1 6 1Fr1,Fr3,Sw4
I
1 7 1 Sw3
|
1 8 1Fr9, Frl 7
1
1 9 IFrl2,Fr4
|
1 50 1 Fr7,N1,UK8,UK9
|
1 1 1Swl,UK5,Fr20 ,030
1
I 2 |G3**
|
1 3 |G15,It3,G26,G31*** |
1 4 1G7,G8,UK4,G19
1
1 5 IG11,G16,G18, Frl5*** I
1 IG23,G28,G32***
1
t 6 1FR10.G1
|
1 7 |Fr8,G4,It2,G2,UK12 1
1 8 1Fr6,B1,Fr22***
|
1 9 |Fr2,It4,Frl9 ,Fr21
1
! 60 1G5,G13,G25,G28,It6
1
I 1 1G9,G10,G12,G17,G 2 0,G22|
1 2 1G6,UK6,G21,B2,G29
1
1 3 1Frl3, UK7,Fr18
1
1 4 1 Sw5
I
1 5 1Fr5,UK11 1 6 IUK3, UK.10,UK14*** 1 7 1 It5
1 i 1
1 8 1 UK13 1 9 I G24 | 70 1 111
1 1 1 |
1 2|
|
| 31 11 1 Total 179
1
(
11
i
NORTH AMERICA
! | REST OF WORLD
US24*
1 1 1
C3,US2 7
1 1
US13, US29,US40
1
C2,US19
1
C1,C5,US5,US7,US28,US35 !
C4 ,U S3 ,US9
1
C7,C9,US8 ,USl1,US21,US31 !
C6,US22,US26
1
US1 US12 US1 6
1 1 IY2, Cz2
US10, US3 2 US4
1 1
CIO, US37
I Jap 1,Y1
US 1 8 , (JS3 3***
I Y3
US2,US17,US20 ,US34
1
1
US36***
1
iCzl
US2 3
1Jap2,Y4
US39 C8 US6 US38 US30
1 1 1 1 1 1 I Jap3
1 1 1
1
1 |
|
1
47****
1 |9
1
* Cholangiosarcoma (US24) ** Aerosol can filler (G3)
*** Frl5 & 22, G31 & 32, UK14, US33 & 36 are still alive, so Ear as known
**** Does not include Canll or 12, or US41: details not known
WPX/ASL2 - LANGIOCASES,22
GENC 008241
Page 48
WPX/ASL2 - LANGI0CASES,21
(Review date. 1 January 1988)
TABLE 8 WESTERN EUROPE FVC PRODUCERS - START-UP DATES vs ASL CASES (OMITTING 0)3 & It.01)
1 START-UP | OOUNTRY NAME | 0CMPANY NAME 1
LOCATION
I .ASL CASE NUMBER |
YEAR OF
;
I YEAR |
1
1 1931 IWest Germany IRASF
1 1933 IWest Germany IWacker
1 |Ludwigshafen |Burghausen
I
| 1st Exposure
|
!1
1
104,07,11,15,23,24(57,54,55,53,55,69,60,531
1 I 1938 |Italy I 1939 I France
1 IMontecatini
1 |Acna
|Ehone-Poulenc/ I St Fons
125,31,32
1 103,09,10,11,14
|55
1 146,48,56,41,43,
|
1 |
1 | Chloe/Atochem 1
115,16,17
I 1940 I United Kingdcm|ICI/EVC
|Runcorn (Closed 1948)
155,41,48 |
I ;
I United Kingdom | ICI/EVC
IHillhouse
101,04,12
|44,54,57
|
I 1945 I Sweden
|Kemanord/Nobel |Sundsvall(Stockvik) 101,02,03,04,05 151,45,47,46,64
!
1 1946 1 France
|Khone-Poulenc I Roussillon
|01
|46
|
I 1948 I United KingdomIBP Chem/ICI/EVC|Barry
103,05,06,07,08,09)66,51,62,63,50,50
I
1I | Vfest: Germany ICWH/Huls
1 |Marl
110,11,13,14 109,10,26,29
|66,65,68,66 161,61,53,62
I |
1 1949 IBelgitm
|Solvay
IJemeppe
101,02
|58,62
|
I 1950 |France
IPCUK/ Atochan IBrignoud
|02,04,05,06,12,19|59,49,65,58,49,59,51 I
11
1
120 |
|
I France
|Rhone-Poulenc/ I St Auban
107,22
|50,58
|
1 I Holland I Norway
IChloe/AtochOT |Shell |Norsk
1 IPemis, Rotterdam IHeroya, Porsgrunn
1 1 |01
1 1 150
1 1 !
1 1951 1 Switzerland I 1952 1 Italy
|Italy
llonza/ ICI/EVC I Sins
| Montedison
ITemi
IMontedison/EVC I Porto Marghera
1 1 |02,06
1 1 157,60
1 ! 1
1 1953 I Austria
|Halvic/Solvay IHallein
1
1
1
|France
ISolvay
ITavaux
108,13,18
157,63,63
|
I Italy
ISolvay
I Ferrara
103
|53
|
I Spain
|Rio Rodano
| United Kingdar IBXL/ BIP/N0RSK
I Vfest Germany IHoechst
IHemani lAycliffe IGendorf
1 1 118
1 1 |55
! 1 |
1 1954 I Vfest Germany IDynanit
| Troisdorf
|01,02,08,12,16,17|56,57,54,61,55,61,
1
11
1
1 1955 I Spain
|Monsanto Iberis IMonzon
1 1956 | Spain
ICaiqsa
ISabinanigo
1 |Hispavic/Solvay | Torrelavega
I 1958 | Vfest Germany ISolvay
IRheinberg
I 1960 I Italy
|S C Ravenna/EVC I Ravenna
|19,20,21,22,27,30|54,61,62,61,55,51
11 11 11 11 |04 |59
|
1 1 1 1 |
IVfest Germany ILonza/ICI/EVC I Waldshnt
|06,13,8
|62,60,60
|
I 1961 I Italy I 1962 1 Portugal I 1965 I France
| Montedison/EVC |Brindisi
1 CLres
I Oporto
|Rhone-Poulenc IMontlucon
1
1 121
1
1 |59
1
1 |
I Italy I Italy
|Pozzi |Pensac
|Ferrandina IMira, Venice
1 105
1 |67
1 |
IVfest Germany IWdcker
I Cologne
1
1
1
1 1966 IWest Germany IHoechst
| Knapsack( Frankfurt 105*
|60
|
I 1967 |France I Spain
lAtochem |Rio Rodano
IBalan |Miranda de Ebro
1 1
1 1
1 1
I Greece
|Esso Pappas
IDiavata Salonika 1
1
1
1 1968 I Belgium
IBadiphil
|Antwerp
1 1969 I United Kingdon I Vinatex/Norsk |Staveley
I Italy
|Rumanica/EVC | Cagliari Sardina
1 1 I
1 1 I
1 1 1
Continued
GENC 008242
Table 8 - Continued WESTERN EUROPE PVC PRODUCERS - START IP DATES vs ASL CASES (OMHTINS GOT & It.Ql)
I START-UP | COUNTRY NAME | OOMPANY NAPE 1
LOCATION
| YEAR 1 1 1970 |Italy
1
| SIR
1 I Porto Torres Sar
I United Kingdom! ICI/EVC
I Runcorn
1 1971 I Spain
|Hispavic/Solvay|Martorell
1 Sweden
|Krmanord/Norsk 1Stenungsund
(United Kingdom IBP Qian
IBaglan Bay
1 1972 I Finland
IPekana
ISvartback
I Holland
|DSM
|Beek Limburg
I 1976 I France
|Soc Art D'vinyl|Mazingarbe
1
1 (CDF)
|
1 1977 I Spain
|Monsanto Iberial Tarragona
1 1982 IWest Germany 1ICI/EVC
IVoslapp
11
|Wilhelmshaven
1 ASL CASE NUMBER | 11 11 11 11 11 11 11 I1 11
11
11 11 11
YEAR OF 1st Exposure
* Laboratory worker in Research Department
WPX/ASL2 - LANGIOCASES,24
GENC 00S24
v hi . it'w (late i January
TABLE 9
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
|START-UP I COMPANY NAME
1 YEAR 1 1 1939? |*UCC
| LOCATION
1 1 S Charleston
I ASL CASE 1 YEAR OF
I NUMBER
1 1st EXPOSURE
107,13,19,21,24, 144,42,43,46,39,
1 | Dow
1 I 1940? |*BFG
1 | Midland (made
1 Saran copolymer) | Louisville
127,28,29,31,35 141,44,42,46,44 11 |1 101,02,03,04,05, 148,55,45,52,44,
1 1 106,09,16,17,22, 162,45,50,55,47,
1 I 1946 |*UCC/Dow 1 1947 | Goodyear 1 1948 I Firestone/
1 126,33,34,37,40 147,54,55,53,42
| Texas City (Partially closed 1977) 1
| Niagara Falls
108,10,11,20,41 146,51,46,55,?
| Pottstown
|12
|49
I Occidental | Uniroyal
| | Painesville
1 1
1 1
1 ] 1950 | Monsanto
1 (closed 1975) | Springfield
1 |32
1 151
1 1 1952 | Dow
I BFG
1 (Closed 1975
1
l Midland (No PVC since c 1975)
| Avon Lake
| 18
1
1 154
1 1953 | Diamond/BFG
| Deer Park
1 1954 | General Tire/ ** 1 Ashtabula
| |36
1 i 56
| DiversiTech
| (Closed 1984. Reopened 1986 by Vygen)
1 1956 I Air Products
| Pensacola (Pace) 1
I Atlantic Refining -| Brooklyn(Closed late 1960s)
1 Borden
| Leominster (Closed 1984)
1 1 1
| Conoco
1 Hebronville (Closed 1975)
1
| BFG | Great American
| Niagara | Fitchburg
| 12 3
1 158
I PIastics
| (Closed 1983)
|
1
1 Hooker
| Hicksville (Closed 1980-81)
1
| Pantasote
| Passaic(Closed 1984) 39
160
1 1957 1 Atlantic Tubing | Tenneco/
| Cranston (Closed 1967)
| Flemington NJ
130
1 159
! Occidental 1 1958 | Keysor Century
I Air Products
1 (Closed 1985)
1
1 Saugus, Cal
|
| Calvert City(Paducah)
38
1 1 |63
1 1 19 60 1 BFG
1 (Closed March 1982 Re-opened October 1983)
| Long Beach, Cal (No PVC now.
1
1 1 Formerly shown as Watson)
1 Borden
1 Illiopolis
|
1 1962 1 Tenneco/Occidental 1 Burlington NJ
)
1 1 1
1 1963 I Conoco/Vista
1 Aberdeen, Miss
|!
1
I Stauffer
| Long Beach, Cal (Closed 1982)
1
1 1965 I Conoco/Olin
| Assonet, Mass (Closed by Olin 1975)
I Ethyl
| Baton Rouge (Closed 1984)
1
1 1966 I Diamond/Georgia | Delaware City
1
1
i 1 Gulf
|
11
|Gen Tire/Pantasote ] Mt Pleasant W Va |(Closed 1982) 1
I BFG
| Henry, 111
1
1
| Stauffer/Formosa 1 Delaware City (Sold to Formosa 198 1)
1 1967 I Allied/Robintech/ | Painesville, 0. (No PVC made by Robintech.
1 Georgia Pacific | GP converted to polystyrene)
1
I Hooker/Occidental | Burlington NJ
1
1 1968 IFirestone/Occidental Perryville (Closed 1982)
1 1
--
37PX/ASL2 - LANGIOCASES , 25
Continued
GENC 0Q8244
TABLE 9 (Continued)
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP 1 YEAR | 1969 |
1971 1972 1973 1974
1 | | | |
197 5
1
1 1
1979
1 1 1 |
1983 1986
1 |
|
COMPANY NAME
BFG
Goodyear/BFG
Conoco/Vis ta
Nat Starch
Borden
Atlantic Tubing/
Tallyrand
Shintech
Certain-teed
Georgia Pacific/
Georgia Gulf
Tenneco/Occidental
Firestone/
Occidental
Formosa
V yg e n
**
LOCATION
Pedricktown NJ Plaquemine
| ASL CASE 1 NUMBER | |
Oklahoma City Meredosia, 111 Springfield
| | |
Cranston RI (Closed 1982)
Freeport, Tex Lake Charles Plaquemine, La
1 | | |
Pasadena, Tex
1 |
Addis (formerly shown as
Plaquemine)
|
Point Comfort, Tex|
Ashtabula, Ohio |
1 YEAR OF
|
1 1st EXPOSURE |
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
* My databank has no information on UCC before 1946 or BFG before 1950 ** Refer to same plant at Ashtabula, bought by Vygen from DiversiTech.
h'B Some of the plants in this list were closed down, some have changed ownership over the years, some have changed their product.
WPX/ASL2 - LANGIOCASES,26
GENC 008245
Page 5 2
(Review date 1 January 1988)
TABLE 10 CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP| YEAR |
1 1943 |
(1941?) 1
1951
1 1 |
19 57
1 1 I
1966
1 1 |
1979
1 ! I
1
COMPANY NAME
|
1
Goodrich (Formerly Gulf)
1 |
|
Monsanto
I 1 1
Goodrich
1 1 |
Esso (Imperial Oil)
1
1 |
Diamond Shamrock BF Goodrich
1 1 Alb/| |
LOCATION
1 ASL CASE 1 NUMBER
Shawinigan
1 101,02, 03,04,05 106,07, 08,09,10 111,12
1 La Salle (Closed 1975)
1
I Welland (? Niagara)
Sarnia Fort Saskatchewan
1 1 1 1 1 1 1
I YEAR OF 1 1st EXPOSURE
1 |44,43 41 45,44, 147,46 61 46,53
1?,? 1 1 1 1 I 1 1 1 1 1 ! 1
WPX/ASL2 - LANGIOCASES,27
SENC 008246
Page 53
(Review date 1 January 1988)
TABLE 11
EASTERN BLOC PVC FACTORIES - START-UP DATES vs ASL CASES
START-UP I COUNTRY NAME | COMPANY NAME
YEAR
Pre 1939 I East Germany |State Company
1941 I Prussia
|State Comps
1950 |Yugoslavia
I Jugo Vini1
1951 |Czechoslovakia |State Comps
19 55 |East Germany |State Comps
1956 |Rumania
|State Comps
1957 ]Poland
|State Comps
|Rumania
|State Comps
1958 19 59 1961 1963 1965 1967 19 69 1970
1972 1975
19 76 1977
|Rumania
[State Comps
I Hungary
|State Comps
1 Rumania
|State Comps
|Yugoslavia
| Ohis
I Bulgaria
|State Comps
I Poland
|State Comps
I Ru s s i a
|State Comps
1 Rumania
|State Comps
1 Ru s s i a
|State Comps
1 Yugoslavia
|Vinilplastika
1 Czechoslovakia |State Comps
|Russia
|State Comps
I Yugoslavia
1 Hip
|Rumania
|State Comps
| LOCATION
1 | Schopau )Vladimir et al 1 Split |Novaky |Bitterfeldt |Icechim lOsweicim (Dwory) ITirnaveni 1Turda |Risnov IBerente Borsod IBorzesti |Skopj e I Varna I Tarnow ID]erjinsk IRimnicu Vilcea [Volgograd | Zadar |Neratovice IKalush Area |Pancevo IRimnicu Vilcea
1 ASL CASE | NUMBER
1 1 101,02,03,04 101,02
1 1 1 1 1 i 1 1 1 1 1 1 1 1 1 1 1 1 1
1 YEAR OF I 1st Exposure
1 1 153,50,54,48 157,50 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
WPX, AS L2 - i.ANGIOCASES, 28
6ENC 008247
Page 54
(Review date 1 January 1988)
TABLE 12
JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES
|START-UP | I YEAR 1 1950 |
| 1 1 1951 1 1 1952 | | 1 1951 I | | 1 1955 | 1 1956 I | 1 1957 | | 1 1960 | | I 1964 | 1 1966 I 1 1967 | | I 1968 I | I 1970 | I | I | | I 1 1971 | 1 1973 | | 1974 I
COMPANY NAME
Chisso Corp Kanegafuchi Kag Tekkosha Mitsui Toatsu Mitsubishi Mon Sumitomo Kag Denki Kagaku Nippon Zeon Toa Gosei Ryo-Nichi Nippon Zeon Nissbin Kagaku Kureha Kasei. Shinetsu Kag Denki Kagaku Kanegafuchi Kag Chisso Corp Tokuyama Seksui San Arrow Kagak Sumitomo Kag Ryo-Nichi Shinetsu Kag Chisso Corp Denki Kagaku Kanegafuchi Kag Kawasaki Yuki Mitsui Toatsu Nissan Kagaku Shinetsu Kag Tekkosha Asahi Glass Toyo Soda
I 1975 | Central Kagaku I Toyo Soda
1 1977 | Unknown
1 LOCATION
1 | Minamata I Osaka | Sakata | Nagoya 1 Yokkaichi | Klkumoto | Shibukawa 1 Kambara | Tckushima 1 Uozu 1 Takoaka | Takeo I Nishiki I Naoetsu 1 Ohmi | Takasago | Chiba 1 Tokuyama | Tokuyama | Chiba 1 Mlzushima I Tokuyama | Mizushima I Goi (Chiba) | Kashima 1 Kawasaki I Sakai | Chiba 1 Kashima | Yokkaichi | Hayatsuki | Sakata I Yokkaishi 1 Kawasaki | Yokkaichi | Kashima
1 ASL CASE | NUMBER
1 | 02 1 I 01, 03
1 1 1 1 1 1 ! 1 1 1 1 1 I 1 1 1 1 1 1 ! 1 1 1 1 1 1 1 1 1 1 1 1
1 YEAR OF 1 1st EXPOSURE 1 1 58 1 1 53,65 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
| |
1
1
WPX/ASL2 - LANGTOCASES,29
GENC 008243
V
Page 5 b
(Review date 1 January 1988)
TABLE 13
SOUTH AND CENTRAL AMERICAN PVC PRODUCERS
START-UP | YEAR |
1953 I 1954 |
1955 1956 1960
| | |
1961 1965
1 | |
1966' | 1967 |
1968 1970
1 | |
1 1971 |
1975 | 1976 |
1977 1978
| !
1979
1 1 I
COMPANY NAME
Monsanto Mexica Policyd Geon Do Brazil Elchlor/Solvay Electroc.hlor Viplastic Indupa PET Columbiana Carburo De Col Plasticos Omega SOC Paramonga Primex Policasa Petro Dow Polimeros Mex Rico Chemicals Petroplas Indust Resistor. Huls Brasil Polychem Policyd PET Camacari
| LOCATION
1
11
| Lecheria (Mexico)
1
I Mexico City (Mexico)
1
| Sao Paulo (Brazil)
1
1 Sao Caetano (Brazil)
1
ICapitan Bermudez(Argentina) 1
| Mendoz (Argentina)
1
| Cinco Saltos (Argentina) 1
1 Cartagena (Colombia) | Medellin (Colombia)
1 1
I Mexico
1
| Paramonga (Peru)
1
| Puebla (Mexico)
1
| Managua (Nicaragua)
1
| Conception (Chile)
1
I St Martin Puebla (Mexico) 1
| Guyanilla (Puerto Rico)
1
I EL Tablazo (Venezuela)
1
1 Tlazcala (Mexico)
1
| Cubato (Brazil)
1
| El Salvador
1
| Coatzacoalcos (Mexico)
1
| Camacari Bahia (Brazil)
1
ASL CASE NUMBER
i YEAR OF
1 1st EXPOSURE 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
WPX/ASL2 - LANGIOCASES,30
j
|
i
GENC 00824?
Page 56
(Review date 1 January 1988)
TABLE 19 AUSTRALASIAN PVC PRODUCERS
START-UP DATES
START-UP YEAR
COMPANY NAME
Mid 1950s
ICl Aust ralia
1960s B F Goodrich
Late 1970s ICI Australia
LOCATION
Botany, Sydney Melbourne Laverton Melbourne
ASL CASE NUMBF.R
YEAR OF 1st EXPOSURE
WPX/ASL2 - LANGTOCASES , 3 1
6ENC 008250
l Page _S7
(Review date 1 January 1988)
TABLE 15 MIDDLE EASTERN PVC PRODUCERS
START-UP DATES
START-UP DATE
Sept 1986
COUNTRY NAME Saudi Arabia
COMPANY NAME
I
LOCATION
National Plastic |Arabian Petrochemical Company
Company
IMadiant
(Ibn Hayan)
|A1-Jubail
IAl-Sinahyah
I
WPX/ASL2 - LANGT.OCASES ,32
GENC 008251
1
CDINTkY AND RKRh.RE.NCK. NO
NAME OR INITIALS
DATE OF BIRTH
t,JU Clll Hi CAI.S POLYMERS
LIVER Aa^i ofa rroina Cases - (Review Date: l Jan 19..)
]2 U
FIRST VC EXPOSURE
DATE OF AC E AT
YEARS OF KXROSURE YEARS OF
DIAGNOSIS DIAGNOSIS TO
EXPOSURE
DIAGNOSIS
DATE OF DEATH
HISTO LOGICAL CONFIRM ATION
ESTIMATED EXPOSURE OCCUPATION LEVEL
OTHER CAREER HIGHLIGHTS
WHX/ASL - LANGIOCASE' OTHER COMMENTS
GENC 003252
